Multidetector computed tomography for preoperative prediction of postsurgical prognosis of patients with extrahepatic biliary cancer

Shogo Kobayashi, Hiroaki Nagano, Shigeru Marubashi, Hiroshi Wada, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Tonsok Kim, Yuichiro Doki, Masaki Mori

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

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Background: Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer.We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). Methods: We retrospectively analyzed 71 patients who underwent MDCT preoperatively and were scheduled for surgical resection of biliary cancer. For MDCT diagnosis, we used MDCT-based classification equivalent to the surgical and pathological classification of the Japanese Society of Biliary Surgery. We evaluated MDCT-related prognostic factors and non-curative surgical factors and compared these factors with pathological results. Results: MDCT-diagnosed category T (primary tumor invasion) included both prognostic factors and non-curative surgical factors but not category N (lymph node metastasis). Multivariate analysis identified MDCT-based suspected arterial invasion as an independent prognostic factor. In patients suspected of arterial invasion by MDCT, the 3-year overall survival rate was only 39% and the curative resection ratio was only 33%, because of the high positive surgical dissected margin. Conclusion: MDCT-based suspected arterial invasion is a predictor of poor prognosis after surgery for biliary cancer and represents a noncurative surgical factor associated with positive dissected margin.

元の言語英語
ページ(範囲)376-383
ページ数8
ジャーナルJournal of Surgical Oncology
101
発行部数5
DOI
出版物ステータス出版済み - 4 1 2010
外部発表Yes

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All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

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