Multifunctional silica-based hybrid nanoparticles for biomedical applications

研究成果: ジャーナルへの寄稿評論記事

2 引用 (Scopus)

抄録

Multifunctional nanoparticles have contributed to several advances in the biomedical field. For example, many have been shown to provide higher level analysis in fundamental studies on cancer and regenerative medicine. Application of multifunctional nanoparticles as contrast agents or probes for diagnostic imaging enables integration of various imaging modalities which provides greater detail and more accurate information for diagnosis. In addition, these multifunctional materials may help researchers and clinicians combine diagnostics and treatment, called theranostics or image-guided therapy, for minimally invasive treatment of metastatic and minute cancers. Based on the viewpoint of the toxicity and the easily-controlled surface characteristics, shape, and internal function of silica-based hybrid nanoparticles, this review describes that the hybrid nanoparticles break ground for various analytical methods for fundamental studies, diagnostic techniques, and therapies. In particular, the present review focuses on seamless imaging, dual-modal imaging, and image-guided therapy using silica-based multifunctional hybrid nanoparticles with visible and near-infrared fluorescence, as well as X-ray-absorbing, photoresponsive, drug-releasing, and photoinduced heat- and reactive oxygen species-generating capabilities.

元の言語英語
ページ(範囲)855-862
ページ数8
ジャーナルJournal of the Ceramic Society of Japan
124
発行部数9
DOI
出版物ステータス出版済み - 9 2016
外部発表Yes

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Silicon Dioxide
Silica
Nanoparticles
silicon dioxide
nanoparticles
Imaging techniques
therapy
cancer
releasing
medicine
toxicity
Contrast Media
Toxicity
Reactive Oxygen Species
drugs
Fluorescence
Infrared radiation
X rays
heat
fluorescence

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Chemistry(all)
  • Condensed Matter Physics
  • Materials Chemistry

これを引用

Multifunctional silica-based hybrid nanoparticles for biomedical applications. / Hayashi, Koichiro.

:: Journal of the Ceramic Society of Japan, 巻 124, 番号 9, 09.2016, p. 855-862.

研究成果: ジャーナルへの寄稿評論記事

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