N-confused porphyrin possessing glucamine-appendants: Aggregation and acid/base properties in aqueous media

Yoshiya Ikawa, Hiroaki Ogawa, Hiroyuki Harada, Hiroyuki Furuta

研究成果: Contribution to journalArticle査読

22 被引用数 (Scopus)

抄録

A water-soluble derivative of N-confused porphyrin (NCP: 5,10,15,20-tetraaryl-2-aza-21-carbaporphyrin) was synthesized by introducing glucamine groups at the para-position of meso-aryl groups. The tetraglucamine-appended NCP (TG-NCP) exists as monocation in aqueous solution containing 6 mM sodium dodecyl sulfate (SDS) but exists as freebase to form aggregates in pure water. These properties are distinct from those of corresponding regular porphyrin, which exists as freebase in the micellar solution and practically insoluble in water.

本文言語英語
ページ(範囲)6394-6397
ページ数4
ジャーナルBioorganic and Medicinal Chemistry Letters
18
24
DOI
出版ステータス出版済み - 12 15 2008

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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