Nanostructures integrated with a nanochannel for slowing down DNA translocation velocity for nanopore sequencing

Xiaoyin Sun, Takao Yasui, Takeshi Yanagida, Noritada Kaji, Sakon Rahong, Masaki Kanai, Kazuki Nagashima, Tomoji Kawai, Yoshinobu Baba

研究成果: ジャーナルへの寄稿学術誌査読

1 被引用数 (Scopus)

抄録

Here, we developed a device integrated with a nanochannel and nanostructures to slow DNA translocation velocity. We found that translocation velocity of a single DNA molecule inside a nanochannel was decreased by pre-elongating it using some nanostructures, such as a shallow channel or nanopillars. This decrease of the translocation velocity was associated with the DNA mobility change, which is an intrinsic parameter of DNA molecules and unaffected by an electric field.

本文言語英語
ページ(範囲)735-738
ページ数4
ジャーナルanalytical sciences
33
6
DOI
出版ステータス出版済み - 2017

!!!All Science Journal Classification (ASJC) codes

  • 分析化学

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