Nanowire devices for exosomal MicroRNA extraction

Satoru Ito, Takao Yasui, He Yong, Takeshi Yanagida, Sakon Rahong, Masaki Kanai, Kazuki Nagashima, Hiroshi Yukawa, Noritada Kaji, Tomoji Kawai, Yoshinobu Baba

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

We fabricated nanowire devices, which had zinc oxide (ZnO) nanowires embedded in microchannels on PMMA substrate, to isolate exosomes from cell culture supernatant and extract MicroRNA (miRNA) from the isolated exosomes. The exosomes could be trapped by nanowires without any capturing molecules, such as antibodies against the exosomes. The exosomal miRNA could be extracted efficiently with little loss of the miRNA amount, which is comparable to that using a conventional method to extract miRNA from the exosomes.

本文言語英語
ホスト出版物のタイトル17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
出版社Chemical and Biological Microsystems Society
ページ1887-1889
ページ数3
ISBN(印刷版)9781632666246
出版ステータス出版済み - 2013
外部発表はい
イベント17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, ドイツ
継続期間: 10 27 201310 31 2013

出版物シリーズ

名前17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
3

その他

その他17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
国/地域ドイツ
CityFreiburg
Period10/27/1310/31/13

All Science Journal Classification (ASJC) codes

  • バイオエンジニアリング

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