TY - JOUR
T1 - Naturally occurring chromone glycosides
T2 - Sources, bioactivities, and spectroscopic features
AU - Amen, Yhiya
AU - Elsbaey, Marwa
AU - Othman, Ahmed
AU - Sallam, Mahmoud
AU - Shimizu, Kuniyoshi
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/12/1
Y1 - 2021/12/1
N2 - Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti‐inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed13C‐NMR data of compounds 1–192, have been added, except for those that have no reported13C‐NMR data.
AB - Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti‐inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed13C‐NMR data of compounds 1–192, have been added, except for those that have no reported13C‐NMR data.
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U2 - 10.3390/molecules26247646
DO - 10.3390/molecules26247646
M3 - Review article
C2 - 34946728
AN - SCOPUS:85121424245
SN - 1420-3049
VL - 26
JO - Molecules
JF - Molecules
IS - 24
M1 - 7646
ER -