Nectrianolins A, B, and C, new metabolites produced by endophytic fungus Nectria pseudotrichia 120-1NP

Nanang Rudianto Ariefta, Priska Kristiana, Handojo Hadi Nurjanto, Hiroyuki Momma, Eunsang Kwon, Tatsuya Ashitani, Keitaro Tawaraya, Tetsuya Murayama, Takuya Koseki, Hiroshi Furuno, Narandulam Usukhbayar, Ken ichi Kimura, Yoshihito Shiono

    研究成果: Contribution to journalArticle査読

    4 被引用数 (Scopus)

    抄録

    Two sesquiterpene-epoxycyclohexenone conjugates, nectrianolins A (1) and B (2), together with a sesquiterpene, nectrianolin C (3), were isolated from the brown rice culture of Nectria pseudotrichia 120-1NP, an endophytic fungus isolated from Gliricidia sepium. Their structures were determined on the basis of 1D-/2D-NMR spectroscopy and HRESIMS data analyses in combination with chemical means. Nectrianolins A–C (1–3) exhibited cytotoxic activity against both HL60 and HeLa cells.

    本文言語英語
    ページ(範囲)4082-4086
    ページ数5
    ジャーナルTetrahedron Letters
    58
    43
    DOI
    出版ステータス出版済み - 1 1 2017

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry

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