Neural stem cell therapy aiming at better functional recovery after spinal cord injury

Yicheng Zhu, Naohiro Uezono, Tetsuro Yasui, Kinichi Nakashima

研究成果: ジャーナルへの寄稿評論記事

11 引用 (Scopus)

抄録

Injury to the spinal cord causes transection of axon fibers and neural cell death, resulting in disruption of the neural network and severe functional loss. Reconstruction of the damaged neural circuits was once considered to be hopeless as the adult mammalian central nervous system has very poor ability to regenerate. For this reason, there is currently no effective therapeutic treatment for spinal cord injury (SCI). However, with recent developments in stem cell research and cell culture technology, regenerative therapy using neural stem cell (NSC) transplantation has rapidly been developed, and this therapeutic strategy makes it possible to rebuild the destroyed neural circuits. In this review, we discuss the recent breakthroughs in NSC transplantation therapy for SCI. Developmental Dynamics 247:75–84, 2018.

元の言語英語
ページ(範囲)75-84
ページ数10
ジャーナルDevelopmental Dynamics
247
発行部数1
DOI
出版物ステータス出版済み - 1 2018

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Neural Stem Cells
Cell- and Tissue-Based Therapy
Spinal Cord Injuries
Stem Cell Transplantation
Stem Cell Research
Therapeutics
Axons
Cell Death
Central Nervous System
Cell Culture Techniques
Technology
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Developmental Biology

これを引用

Neural stem cell therapy aiming at better functional recovery after spinal cord injury. / Zhu, Yicheng; Uezono, Naohiro; Yasui, Tetsuro; Nakashima, Kinichi.

:: Developmental Dynamics, 巻 247, 番号 1, 01.2018, p. 75-84.

研究成果: ジャーナルへの寄稿評論記事

Zhu, Yicheng ; Uezono, Naohiro ; Yasui, Tetsuro ; Nakashima, Kinichi. / Neural stem cell therapy aiming at better functional recovery after spinal cord injury. :: Developmental Dynamics. 2018 ; 巻 247, 番号 1. pp. 75-84.
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