抄録
Introduction: Self- and external-preoccupation have been linked to psychopathological states. The neural substrates underlying self- and external-preoccupation remain unclear. In the present study, we aim to provide insight into the information-processing mechanisms associated with self- and external-preoccupation at the structural level. Methods: To investigate the neural substrates of self- and external-preoccupation, we acquired high-resolution T1-weighted structural images and Preoccupation Scale scores from 1,122 young subjects. Associations between regional gray matter volume (rGMV) and Preoccupation Scale subscores for self- and external-preoccupation were estimated using voxel-based morphometry. Results: Significant positive associations between self-preoccupation and rGMV were observed in widespread brain areas such as the bilateral precuneus and posterior cingulate gyri, structures known to be associated with self-triggered self-reference during rest. Significant negative associations between external-preoccupation and rGMV were observed only in the bilateral cerebellum, regions known to be associated with behavioral addiction, sustained attention, and reward system. Conclusion: Our results reveal distinct neural substrates for self- and external-preoccupation at the structural level.
本文言語 | 英語 |
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論文番号 | e01267 |
ジャーナル | Brain and Behavior |
巻 | 9 |
号 | 6 |
DOI | |
出版ステータス | 出版済み - 6月 2019 |
外部発表 | はい |
!!!All Science Journal Classification (ASJC) codes
- 行動神経科学