Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship

Masafumi Kaneko, Koji Yamada, Tomofumi Miyamoto, Masanori Inagaki, Ryuichi Higuchi

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

抄録

The effects of the gangliosides isolated from echinoderms on the neuritogenesis of a rat pheochromocytoma cell line (PC-12 cells) in the presence of nerve growth factor were investigated. The results show that they displayed neuritogenic activity. Based on the observed results, a structure-activity relationship has been established.

元の言語英語
ページ(範囲)462-463
ページ数2
ジャーナルChemical and Pharmaceutical Bulletin
55
発行部数3
DOI
出版物ステータス出版済み - 3 1 2007

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Gangliosides
PC12 Cells
Nerve Growth Factor
Structure-Activity Relationship
Rats
Cells

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

これを引用

Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship. / Kaneko, Masafumi; Yamada, Koji; Miyamoto, Tomofumi; Inagaki, Masanori; Higuchi, Ryuichi.

:: Chemical and Pharmaceutical Bulletin, 巻 55, 番号 3, 01.03.2007, p. 462-463.

研究成果: ジャーナルへの寄稿記事

Kaneko, Masafumi ; Yamada, Koji ; Miyamoto, Tomofumi ; Inagaki, Masanori ; Higuchi, Ryuichi. / Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship. :: Chemical and Pharmaceutical Bulletin. 2007 ; 巻 55, 番号 3. pp. 462-463.
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