New halogenated C15 acetogenins from Okinawan sea hare Aplysia dactylomela

Koushi Matsuyama, Tomoe Inoue, Tomoki Muroga, Naomichi Arima, Matsumi Doe, Fumito Tani, Yuka Ookawa, Yuuka Okamoto, Satoaki Onitsuka, Hiroaki Okamura, Tetsuo Iwagawa, Toshiyuki Hamada

研究成果: ジャーナルへの寄稿学術誌査読

抄録

Two new C15 acetogenins 1 and 2, along with four known sesquiterpenes isolaurenisol (3), laurokamurene D (4), itomanol (5), and acetylelatol (6), were isolated from sea hare Aplysia dactylomela. The structures, including the relative stereochemistries, of 1 and 2 were determined based on spectroscopic evidence. Finally, the in vitro cytotoxicities of the six compounds against S1T cells, an adult T-cell leukemia cell line, were evaluated.

本文言語英語
論文番号132889
ジャーナルTetrahedron
DOI
出版ステータス印刷中 - 2022

!!!All Science Journal Classification (ASJC) codes

  • 生化学
  • 創薬
  • 有機化学

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