New polyketides, paralactonic acids A–E produced by Paraconiothyrium sp. SW-B-1, an endophytic fungus associated with a seaweed, Chondrus ocellatus Holmes

Takuma Suzuki, Nanang Rudianto Ariefta, Takuya Koseki, Hiroshi Furuno, Eunsang Kwon, Hiroyuki Momma, Desi Harneti, Rani Maharani, Unang Supratman, Ken ichi Kimura, Yoshihito Shiono

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

抄録

Five polyketides, paralactonic acids A-E (1–5) were isolated from Paraconiothyrium sp. SW-B-1, an endophytic fungus isolated from the seaweed, Chondrus ocellatus Holmes. Their structures were determined by various spectroscopic methods, predominantly by 2D NMR spectroscopic analyses. The absolute configurations of compounds 1–5 were determined by comparison of the experimental and calculated ECD spectra. Compound 5 showed moderate antibacterial activity and restored the growth of a mutant yeast strain inhibited by hyperactivated Ca 2+ -signaling.

元の言語英語
ページ(範囲)75-81
ページ数7
ジャーナルFitoterapia
132
DOI
出版物ステータス出版済み - 1 1 2019

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Chondrus
Polyketides
Seaweed
Fungi
Yeasts
Acids
Growth

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

これを引用

New polyketides, paralactonic acids A–E produced by Paraconiothyrium sp. SW-B-1, an endophytic fungus associated with a seaweed, Chondrus ocellatus Holmes. / Suzuki, Takuma; Ariefta, Nanang Rudianto; Koseki, Takuya; Furuno, Hiroshi; Kwon, Eunsang; Momma, Hiroyuki; Harneti, Desi; Maharani, Rani; Supratman, Unang; Kimura, Ken ichi; Shiono, Yoshihito.

:: Fitoterapia, 巻 132, 01.01.2019, p. 75-81.

研究成果: ジャーナルへの寄稿記事

Suzuki, T, Ariefta, NR, Koseki, T, Furuno, H, Kwon, E, Momma, H, Harneti, D, Maharani, R, Supratman, U, Kimura, KI & Shiono, Y 2019, 'New polyketides, paralactonic acids A–E produced by Paraconiothyrium sp. SW-B-1, an endophytic fungus associated with a seaweed, Chondrus ocellatus Holmes', Fitoterapia, 巻. 132, pp. 75-81. https://doi.org/10.1016/j.fitote.2018.11.017
Suzuki, Takuma ; Ariefta, Nanang Rudianto ; Koseki, Takuya ; Furuno, Hiroshi ; Kwon, Eunsang ; Momma, Hiroyuki ; Harneti, Desi ; Maharani, Rani ; Supratman, Unang ; Kimura, Ken ichi ; Shiono, Yoshihito. / New polyketides, paralactonic acids A–E produced by Paraconiothyrium sp. SW-B-1, an endophytic fungus associated with a seaweed, Chondrus ocellatus Holmes. :: Fitoterapia. 2019 ; 巻 132. pp. 75-81.
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abstract = "Five polyketides, paralactonic acids A-E (1–5) were isolated from Paraconiothyrium sp. SW-B-1, an endophytic fungus isolated from the seaweed, Chondrus ocellatus Holmes. Their structures were determined by various spectroscopic methods, predominantly by 2D NMR spectroscopic analyses. The absolute configurations of compounds 1–5 were determined by comparison of the experimental and calculated ECD spectra. Compound 5 showed moderate antibacterial activity and restored the growth of a mutant yeast strain inhibited by hyperactivated Ca 2+ -signaling.",
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AU - Ariefta, Nanang Rudianto

AU - Koseki, Takuya

AU - Furuno, Hiroshi

AU - Kwon, Eunsang

AU - Momma, Hiroyuki

AU - Harneti, Desi

AU - Maharani, Rani

AU - Supratman, Unang

AU - Kimura, Ken ichi

AU - Shiono, Yoshihito

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