New vertebral compression fractures after prophylactic vertebroplasty in osteoporotic patients

Hironori Kamano, Hiwatashi Akio, Nobuo Kobayashi, Sokun Fuwa, Osamu Takahashi, Yukihisa Saida, Hiroshi Honda, Yuji Numaguchi

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

抄録

OBJECTIVE. Previous studies have shown the possible efficacy of prophylactic cement injection for nonfractured vertebrae during percutaneous vertebroplasty for compression fractures. The purpose of this study was to investigate risk factors for subsequent fractures after prophylactic percutaneous vertebroplasty. MATERIALS AND METHODS. This retrospective study included 116 patients with osteoporotic compression fractures who underwent prophylactic percutaneous vertebroplasty. The patients were monitored with physical examinations and radiographs at 1 day and at 3 and 12 months after percutaneous vertebroplasty, and if back pain recurred. We analyzed the following multiple covariates to determine whether they were associated with recurrence: age, sex, steroid use, and the preoperative number of unhealed or chronic compression fractures. RESULTS. Subsequent fractures in any vertebra occurred within 3 months after the procedure at 26 vertebrae in 21 patients (18.1%), and 36 occurred in 28 patients (24.1%) within 12 months. The occurrence of subsequent fractures within 12 months depended on the preoperative number of unhealed vertebrae: the occurrence rate was 16.9% (11/65) for one vertebra, 27.0% (10/37) for two vertebrae, and 50.0% (7/14) for three or more vertebrae. The incidence of subsequent fractures was significantly higher in patients with three or more fractures than in those with one fracture (p < 0.05). There were no statistically significant differences for the other factors. CONCLUSION. Patients with three or more fractures tended to have subsequent fractures, despite undergoing prophylactic percutaneous vertebroplasty. However, there was no increased risk of subsequent fractures related to prophylactic percutaneous vertebroplasty.

元の言語英語
ページ(範囲)451-456
ページ数6
ジャーナルAmerican Journal of Roentgenology
197
発行部数2
DOI
出版物ステータス出版済み - 8 1 2011

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Vertebroplasty
Compression Fractures
Spine
Osteoporotic Fractures
Back Pain
Physical Examination
Retrospective Studies
Steroids
Recurrence
Injections
Incidence

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

これを引用

New vertebral compression fractures after prophylactic vertebroplasty in osteoporotic patients. / Kamano, Hironori; Akio, Hiwatashi; Kobayashi, Nobuo; Fuwa, Sokun; Takahashi, Osamu; Saida, Yukihisa; Honda, Hiroshi; Numaguchi, Yuji.

:: American Journal of Roentgenology, 巻 197, 番号 2, 01.08.2011, p. 451-456.

研究成果: ジャーナルへの寄稿記事

Kamano, H, Akio, H, Kobayashi, N, Fuwa, S, Takahashi, O, Saida, Y, Honda, H & Numaguchi, Y 2011, 'New vertebral compression fractures after prophylactic vertebroplasty in osteoporotic patients', American Journal of Roentgenology, 巻. 197, 番号 2, pp. 451-456. https://doi.org/10.2214/AJR.10.5937
Kamano, Hironori ; Akio, Hiwatashi ; Kobayashi, Nobuo ; Fuwa, Sokun ; Takahashi, Osamu ; Saida, Yukihisa ; Honda, Hiroshi ; Numaguchi, Yuji. / New vertebral compression fractures after prophylactic vertebroplasty in osteoporotic patients. :: American Journal of Roentgenology. 2011 ; 巻 197, 番号 2. pp. 451-456.
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abstract = "OBJECTIVE. Previous studies have shown the possible efficacy of prophylactic cement injection for nonfractured vertebrae during percutaneous vertebroplasty for compression fractures. The purpose of this study was to investigate risk factors for subsequent fractures after prophylactic percutaneous vertebroplasty. MATERIALS AND METHODS. This retrospective study included 116 patients with osteoporotic compression fractures who underwent prophylactic percutaneous vertebroplasty. The patients were monitored with physical examinations and radiographs at 1 day and at 3 and 12 months after percutaneous vertebroplasty, and if back pain recurred. We analyzed the following multiple covariates to determine whether they were associated with recurrence: age, sex, steroid use, and the preoperative number of unhealed or chronic compression fractures. RESULTS. Subsequent fractures in any vertebra occurred within 3 months after the procedure at 26 vertebrae in 21 patients (18.1{\%}), and 36 occurred in 28 patients (24.1{\%}) within 12 months. The occurrence of subsequent fractures within 12 months depended on the preoperative number of unhealed vertebrae: the occurrence rate was 16.9{\%} (11/65) for one vertebra, 27.0{\%} (10/37) for two vertebrae, and 50.0{\%} (7/14) for three or more vertebrae. The incidence of subsequent fractures was significantly higher in patients with three or more fractures than in those with one fracture (p < 0.05). There were no statistically significant differences for the other factors. CONCLUSION. Patients with three or more fractures tended to have subsequent fractures, despite undergoing prophylactic percutaneous vertebroplasty. However, there was no increased risk of subsequent fractures related to prophylactic percutaneous vertebroplasty.",
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AU - Kamano, Hironori

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AU - Kobayashi, Nobuo

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AU - Takahashi, Osamu

AU - Saida, Yukihisa

AU - Honda, Hiroshi

AU - Numaguchi, Yuji

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N2 - OBJECTIVE. Previous studies have shown the possible efficacy of prophylactic cement injection for nonfractured vertebrae during percutaneous vertebroplasty for compression fractures. The purpose of this study was to investigate risk factors for subsequent fractures after prophylactic percutaneous vertebroplasty. MATERIALS AND METHODS. This retrospective study included 116 patients with osteoporotic compression fractures who underwent prophylactic percutaneous vertebroplasty. The patients were monitored with physical examinations and radiographs at 1 day and at 3 and 12 months after percutaneous vertebroplasty, and if back pain recurred. We analyzed the following multiple covariates to determine whether they were associated with recurrence: age, sex, steroid use, and the preoperative number of unhealed or chronic compression fractures. RESULTS. Subsequent fractures in any vertebra occurred within 3 months after the procedure at 26 vertebrae in 21 patients (18.1%), and 36 occurred in 28 patients (24.1%) within 12 months. The occurrence of subsequent fractures within 12 months depended on the preoperative number of unhealed vertebrae: the occurrence rate was 16.9% (11/65) for one vertebra, 27.0% (10/37) for two vertebrae, and 50.0% (7/14) for three or more vertebrae. The incidence of subsequent fractures was significantly higher in patients with three or more fractures than in those with one fracture (p < 0.05). There were no statistically significant differences for the other factors. CONCLUSION. Patients with three or more fractures tended to have subsequent fractures, despite undergoing prophylactic percutaneous vertebroplasty. However, there was no increased risk of subsequent fractures related to prophylactic percutaneous vertebroplasty.

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