Non-covalent coating of liposome surface with igg through its constant region

Hikari Sato, Yoshiki Miyashita, Koichi Sasaki, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama

研究成果: ジャーナルへの寄稿学術誌査読

3 被引用数 (Scopus)

抄録

Here we present a liposome non-covalently coated with immunoglobulin G (IgG) by using a peptide ligand to the constant region of IgG. IgG coated on the liposome still maintained binding ability to a complementary antigen protein but it was not recognized by Fcγ receptors (FcγRs) of monocytes. The stealth feature of the IgG-coated liposome may be useful to avoid clearance by macrophages in vivo to extend the blood half-life of the liposome.

本文言語英語
ページ(範囲)770-772
ページ数3
ジャーナルChemistry Letters
47
6
DOI
出版ステータス出版済み - 2018

!!!All Science Journal Classification (ASJC) codes

  • 化学 (全般)

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