Non-covalent coating of liposome surface with igg through its constant region

Hikari Sato, Yoshiki Miyashita, Koichi Sasaki, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

抄録

Here we present a liposome non-covalently coated with immunoglobulin G (IgG) by using a peptide ligand to the constant region of IgG. IgG coated on the liposome still maintained binding ability to a complementary antigen protein but it was not recognized by Fcγ receptors (FcγRs) of monocytes. The stealth feature of the IgG-coated liposome may be useful to avoid clearance by macrophages in vivo to extend the blood half-life of the liposome.

元の言語英語
ページ(範囲)770-772
ページ数3
ジャーナルChemistry Letters
47
発行部数6
DOI
出版物ステータス出版済み - 1 1 2018

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Liposomes
Immunoglobulin G
Coatings
Fc Receptors
Macrophages
Blood
Ligands
Antigens
Peptides
Proteins

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

これを引用

Non-covalent coating of liposome surface with igg through its constant region. / Sato, Hikari; Miyashita, Yoshiki; Sasaki, Koichi; Kishimura, Akihiro; Mori, Takeshi; Katayama, Yoshiki.

:: Chemistry Letters, 巻 47, 番号 6, 01.01.2018, p. 770-772.

研究成果: ジャーナルへの寄稿記事

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AU - Mori, Takeshi

AU - Katayama, Yoshiki

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