Nonlinear multiscale circulation model reproducable linear end-systolic pressure-volume relationship

Takao Shimayoshi, Mitsuharu Mishima, Akira Amano, Tetsuya Matsuda

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

As a well-known property of the heart, many studies has reported that the left ventricular end-systolic pressure-volume relationship (ESPVR) is linear. However, the reason of the linearity is poorly understood. This article presents a multiscale circulation model to be a tool for theoretical analyses on the mechanism of the linearity of ESPVR. The model is composed of three sub-models; a detailed closed-loop lumped-parameter model for cardiovascular system, geometric left ventricle model, a comprehensive ventricular myocyte model. Although the present model integrates nonlinear sub-models, the model can successfully reproduce highly linear ESPVR without any arbitrary modifications.

本文言語英語
ホスト出版物のタイトル2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
出版社Institute of Electrical and Electronics Engineers Inc.
ページ6778-6781
ページ数4
ISBN(電子版)9781424479290
DOI
出版ステータス出版済み - 11 2 2014
外部発表はい
イベント2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, 米国
継続期間: 8 26 20148 30 2014

出版物シリーズ

名前2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

その他

その他2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Country米国
CityChicago
Period8/26/148/30/14

All Science Journal Classification (ASJC) codes

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

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