Nonsegmental vitiligo update

Masutaka Furue, Takafumi Kadono

研究成果: Contribution to journalReview article査読

6 被引用数 (Scopus)

抄録

Nonsegmental vitiligo is an acquired leukoderma characterized by the destruction of melanocytes. Autoimmunity is the most widely accepted hypothesis to explain the pathogenesis of nonsegmental vitiligo. Increased oxidative stress and decreased expression of E-cadherin may facilitate the loss of melanocytes. Because vitiligo preferentially affects cosmetically sensitive regions such as the face, hands, and genital area, it imposes significant psychological and social burdens. In this review, we discuss recent topics in the epidemiology, pathogenesis, genetic background, and therapeutic advances of nonsegmental vitiligo.

本文言語英語
ページ(範囲)173-176
ページ数4
ジャーナルDermatologica Sinica
34
4
DOI
出版ステータス出版済み - 12 1 2016

All Science Journal Classification (ASJC) codes

  • 皮膚病学

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