3E (Energy, Economics and Education) are three concepts of community development, and 3E concepts are interlinked between each other. 3E concept is divided into three levels of regions, remote area or villages, small towns and metropolitan cities, and there are different problems of each region. This paper analyzes the relations between energy, economics and education in the metropolitan and industrial city. Especially the influence of nuclear energy concerning at cost production of the industrial and the contribution of education and research for nuclear energy innovation. This relation can be explained using "S-curve". The results of this study is the comparison between the product involves the use of nuclear energy or not in the production process are explained using "S-curve" and its effect on the global economics.