Oesophageal squamous cell carcinoma with lymphoid stroma - A case report

Masaki Mori, Hiroyuki Matsuda, Hiroyuki Kuwano, Hiroshi Matsuura, Keizo Sugimachi

研究成果: Contribution to journalArticle査読

23 被引用数 (Scopus)


We treated a 70-year-old Japanese man with squamous cell carcinoma of the oesophagus with evidence of lymphoid stroma. The tumour consisted of a main lesion invading the muscular layer of the oesophagus, in association with wide areas of carcinoma in situ. The tumour stroma of the lesion was nondesmoplastic and was uniformly infiltrated mainly by abundant lymphocytes and plasma cells. Immunohistochemically, the lymphocytes consisted of a large number of T lymphocytes and a small number of B lymphocytes. S-100 protein positive cells were marked in the tumour cell nests and necrotic change of tumour cells was frequent. Abundant infiltration of lymphocytes and plasma cells was also wide-spread beneath the carcinoma in situ, together with the lymphoid follicles. Carcinoma with lymphoid stroma can occur not only in the breast, uterine cervix, nasopharynx and stomach but also in the oesophagus.

ジャーナルVirchows Archiv A Pathological Anatomy and Histopathology
出版ステータス出版済み - 9 1989

All Science Journal Classification (ASJC) codes

  • 病理学および法医学


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