Olfactory Event-Related Potentials in Normal Subjects and Patients with Smell Disorders

Hirofumi Harada, Kimio Shiraishi, Toshihiko Kato

    研究成果: ジャーナルへの寄稿学術誌査読

    6 被引用数 (Scopus)

    抄録

    We developed a device to record olfactory event-related potentials (OERP) from the human scalp. Methyl-cyclopentenolone was used as the odorant element. A total of 50 stimuli were delivered. Each stimulus lasted 0.5 sec and was delivered once every three inspirations. Normal OERPs were obtained with this device. The positive peak latencies were approximately 350 msec (P1) and 700 msec (P2), respectively. OERPs were also recorded in 40 patients with smell disorders. A positive response at about 300–400 msec was recorded in 7 patients (all females, 15–59 years old). The other 33 patients showed no response. The high potential area of this positive peak was located in the centro-occipital region of the scalp. The latency and the high potential area of this peak were similar to P1 recorded in normal subjects. The source of this peak was considered identical to that of P1. This may be a response to the trigeminal nerve during odor administration. P2 was not recorded in the patients with smell disorders. P2 may therefore be a response to the olfactory nerve.

    本文言語英語
    ページ(範囲)191-196
    ページ数6
    ジャーナルClinical EEG and Neuroscience
    34
    4
    DOI
    出版ステータス出版済み - 10月 2003

    !!!All Science Journal Classification (ASJC) codes

    • 神経学
    • 臨床神経学

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