On-chip measurement of cellular mechanical properties using moiré fringe

Hirotaka Sugiura, Shinya Sakuma, Makoto Kaneko, Fumihito Arai

研究成果: Contribution to journalConference article査読

4 被引用数 (Scopus)

抄録

This paper proposes the method for mechanical characterization of floating cells on a microfluidic chip. We measured the reactive force of cells on the chip by applying mechanical deformation to the cells. Particularly we focused on the method to improve the sensing resolution of the probe position by using the phase detection of moiré fringe. This method realized approximately ten times higher resolution compared to the previous method. The detailed data suggest some unique characteristics of cells. We discussed the phenomenon seen on the data with a mechanical model, which is based on Heltzian contact theory in the light of stiff nucleus.

本文言語英語
論文番号7139685
ページ(範囲)3513-3518
ページ数6
ジャーナルProceedings - IEEE International Conference on Robotics and Automation
2015-June
June
DOI
出版ステータス出版済み - 6 29 2015
外部発表はい
イベント2015 IEEE International Conference on Robotics and Automation, ICRA 2015 - Seattle, 米国
継続期間: 5 26 20155 30 2015

All Science Journal Classification (ASJC) codes

  • ソフトウェア
  • 制御およびシステム工学
  • 人工知能
  • 電子工学および電気工学

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