TY - GEN
T1 - On-chip multi-sorting using high-speed and high-accuracy flow control
AU - Kasai, Yusuke
AU - Sakuma, Shinya
AU - Arai, Fumihito
N1 - Funding Information:
This study was supported by a Grant-in-Aid from the Impulsing Paradigm Change through Disruptive Technologies Program (ImPACT). REFERENCES [1] S. Li et al, Anal Chem, 85, 5468−5474, 2013 [2] H. Sugino et al, Lab Chip, 10, 2559–2565, 2010 [3] S. Sakuma et al, Lab Chip, 17, 2760-2767, 2017
PY - 2018
Y1 - 2018
N2 - We present the on-chip multi-sorting using high-speed flow control with high-accuracy. The speed and accuracy of flow control are critical to throughput of sorting and the number of sorting branches. However, it was difficult in previous researches to achieve both of high-speed and high-accuracy flow control for the high-throughput multi-sorting. By utilizing the on-chip deal membrane pumps driven by the piezoelectric actuators, we succeeded in accurately controlling the flow containing the target particle with high-accuracy of 3.0 µm in 200-µm-width microchannel. In addition, we achieved the high-speed flow control with the response time of within 50 µs. We demonstrated the on-chip multi-sorting with 11-branches. As the result, we succeeded in multi-sorting with the success rate of 88 % at least.
AB - We present the on-chip multi-sorting using high-speed flow control with high-accuracy. The speed and accuracy of flow control are critical to throughput of sorting and the number of sorting branches. However, it was difficult in previous researches to achieve both of high-speed and high-accuracy flow control for the high-throughput multi-sorting. By utilizing the on-chip deal membrane pumps driven by the piezoelectric actuators, we succeeded in accurately controlling the flow containing the target particle with high-accuracy of 3.0 µm in 200-µm-width microchannel. In addition, we achieved the high-speed flow control with the response time of within 50 µs. We demonstrated the on-chip multi-sorting with 11-branches. As the result, we succeeded in multi-sorting with the success rate of 88 % at least.
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M3 - Conference contribution
AN - SCOPUS:85068861479
T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
SP - 1237
EP - 1238
BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PB - Chemical and Biological Microsystems Society
T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Y2 - 11 November 2018 through 15 November 2018
ER -