Optimization and clinical feasibility of free-breathing diffusion-weighted imaging of the liver: Comparison with respiratory-triggered diffusion-weighted imaging

Yukihisa Takayama, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Daisuke Kakihara, Yasuhiro Ushijima, Nobuhiro Fujita, Takashi Yoshiura, Atsushi Takemura, Makoto Obara, Taro Takahara, Hiroshi Honda

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

抄録

Purpose: We compared the image quality of free-breathing diffusion-weighted imaging (FB-DWI) to that of respiratory-triggered DWI (RT-DWI) after proper optimization. Materials and Methods: Three healthy subjects were scanned to optimize magnetic resonance (MR) parameters of FB-DWI to improve image quality, including spatial resolution, image noise, and chemical shift artifacts. After this optimization, we scanned 32 patients with liver disease to assess the clinical feasibility of the optimized FB-DWI. Of the 32 patients, 14 had a total of 28 hepatocellular carcinomas (HCCs), four had a total of 15 metastatic liver tumors, and the other 14 had no tumor. Qualitatively, we compared the image quality scores of FB-DWI with those of RT-DWI with the Wilcoxon signed-rank test. Quantitatively, we compared the signal-to-noise ratios (SNRs) of the liver parenchyma, lesion-to-nonlesion contrast-to-noise ratios (CNRs) and apparent diffusion coefficient (ADC) values of the liver parenchyma and liver tumor by the paired t-test. Results: The average scores of image quality for sharpness of liver contour, image noise, and chemical shift artifacts were significantly higher for FB-DWI than RT-DWI (P < 0.05). SNRs, CNRs, and ADC values of the liver parenchyma and tumors did not differ significantly between the 2 DWI methods. Conclusion: Compared with RT-DWI, the optimized FB-DWI provided better spatial resolution, fewer artifacts, and comparable SNRs, lesion-to-nonlesion CNRs, and ADC values.

元の言語英語
ページ(範囲)123-132
ページ数10
ジャーナルMagnetic Resonance in Medical Sciences
14
発行部数2
DOI
出版物ステータス出版済み - 1 1 2015

Fingerprint

Respiration
Liver
Signal-To-Noise Ratio
Artifacts
Noise
Neoplasms
Nonparametric Statistics
Liver Diseases
Hepatocellular Carcinoma
Healthy Volunteers
Magnetic Resonance Spectroscopy

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

これを引用

Optimization and clinical feasibility of free-breathing diffusion-weighted imaging of the liver : Comparison with respiratory-triggered diffusion-weighted imaging. / Takayama, Yukihisa; Nishie, Akihiro; Asayama, Yoshiki; Ishigami, Kousei; Kakihara, Daisuke; Ushijima, Yasuhiro; Fujita, Nobuhiro; Yoshiura, Takashi; Takemura, Atsushi; Obara, Makoto; Takahara, Taro; Honda, Hiroshi.

:: Magnetic Resonance in Medical Sciences, 巻 14, 番号 2, 01.01.2015, p. 123-132.

研究成果: ジャーナルへの寄稿記事

Takayama, Yukihisa ; Nishie, Akihiro ; Asayama, Yoshiki ; Ishigami, Kousei ; Kakihara, Daisuke ; Ushijima, Yasuhiro ; Fujita, Nobuhiro ; Yoshiura, Takashi ; Takemura, Atsushi ; Obara, Makoto ; Takahara, Taro ; Honda, Hiroshi. / Optimization and clinical feasibility of free-breathing diffusion-weighted imaging of the liver : Comparison with respiratory-triggered diffusion-weighted imaging. :: Magnetic Resonance in Medical Sciences. 2015 ; 巻 14, 番号 2. pp. 123-132.
@article{6f0b5d20615043369ad0b63789bd2c4f,
title = "Optimization and clinical feasibility of free-breathing diffusion-weighted imaging of the liver: Comparison with respiratory-triggered diffusion-weighted imaging",
abstract = "Purpose: We compared the image quality of free-breathing diffusion-weighted imaging (FB-DWI) to that of respiratory-triggered DWI (RT-DWI) after proper optimization. Materials and Methods: Three healthy subjects were scanned to optimize magnetic resonance (MR) parameters of FB-DWI to improve image quality, including spatial resolution, image noise, and chemical shift artifacts. After this optimization, we scanned 32 patients with liver disease to assess the clinical feasibility of the optimized FB-DWI. Of the 32 patients, 14 had a total of 28 hepatocellular carcinomas (HCCs), four had a total of 15 metastatic liver tumors, and the other 14 had no tumor. Qualitatively, we compared the image quality scores of FB-DWI with those of RT-DWI with the Wilcoxon signed-rank test. Quantitatively, we compared the signal-to-noise ratios (SNRs) of the liver parenchyma, lesion-to-nonlesion contrast-to-noise ratios (CNRs) and apparent diffusion coefficient (ADC) values of the liver parenchyma and liver tumor by the paired t-test. Results: The average scores of image quality for sharpness of liver contour, image noise, and chemical shift artifacts were significantly higher for FB-DWI than RT-DWI (P < 0.05). SNRs, CNRs, and ADC values of the liver parenchyma and tumors did not differ significantly between the 2 DWI methods. Conclusion: Compared with RT-DWI, the optimized FB-DWI provided better spatial resolution, fewer artifacts, and comparable SNRs, lesion-to-nonlesion CNRs, and ADC values.",
author = "Yukihisa Takayama and Akihiro Nishie and Yoshiki Asayama and Kousei Ishigami and Daisuke Kakihara and Yasuhiro Ushijima and Nobuhiro Fujita and Takashi Yoshiura and Atsushi Takemura and Makoto Obara and Taro Takahara and Hiroshi Honda",
year = "2015",
month = "1",
day = "1",
doi = "10.2463/mrms.2014-0032",
language = "English",
volume = "14",
pages = "123--132",
journal = "Magnetic Resonance in Medical Sciences",
issn = "1347-3182",
publisher = "Japan Society of Magnetic Resonance in Medicine",
number = "2",

}

TY - JOUR

T1 - Optimization and clinical feasibility of free-breathing diffusion-weighted imaging of the liver

T2 - Comparison with respiratory-triggered diffusion-weighted imaging

AU - Takayama, Yukihisa

AU - Nishie, Akihiro

AU - Asayama, Yoshiki

AU - Ishigami, Kousei

AU - Kakihara, Daisuke

AU - Ushijima, Yasuhiro

AU - Fujita, Nobuhiro

AU - Yoshiura, Takashi

AU - Takemura, Atsushi

AU - Obara, Makoto

AU - Takahara, Taro

AU - Honda, Hiroshi

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Purpose: We compared the image quality of free-breathing diffusion-weighted imaging (FB-DWI) to that of respiratory-triggered DWI (RT-DWI) after proper optimization. Materials and Methods: Three healthy subjects were scanned to optimize magnetic resonance (MR) parameters of FB-DWI to improve image quality, including spatial resolution, image noise, and chemical shift artifacts. After this optimization, we scanned 32 patients with liver disease to assess the clinical feasibility of the optimized FB-DWI. Of the 32 patients, 14 had a total of 28 hepatocellular carcinomas (HCCs), four had a total of 15 metastatic liver tumors, and the other 14 had no tumor. Qualitatively, we compared the image quality scores of FB-DWI with those of RT-DWI with the Wilcoxon signed-rank test. Quantitatively, we compared the signal-to-noise ratios (SNRs) of the liver parenchyma, lesion-to-nonlesion contrast-to-noise ratios (CNRs) and apparent diffusion coefficient (ADC) values of the liver parenchyma and liver tumor by the paired t-test. Results: The average scores of image quality for sharpness of liver contour, image noise, and chemical shift artifacts were significantly higher for FB-DWI than RT-DWI (P < 0.05). SNRs, CNRs, and ADC values of the liver parenchyma and tumors did not differ significantly between the 2 DWI methods. Conclusion: Compared with RT-DWI, the optimized FB-DWI provided better spatial resolution, fewer artifacts, and comparable SNRs, lesion-to-nonlesion CNRs, and ADC values.

AB - Purpose: We compared the image quality of free-breathing diffusion-weighted imaging (FB-DWI) to that of respiratory-triggered DWI (RT-DWI) after proper optimization. Materials and Methods: Three healthy subjects were scanned to optimize magnetic resonance (MR) parameters of FB-DWI to improve image quality, including spatial resolution, image noise, and chemical shift artifacts. After this optimization, we scanned 32 patients with liver disease to assess the clinical feasibility of the optimized FB-DWI. Of the 32 patients, 14 had a total of 28 hepatocellular carcinomas (HCCs), four had a total of 15 metastatic liver tumors, and the other 14 had no tumor. Qualitatively, we compared the image quality scores of FB-DWI with those of RT-DWI with the Wilcoxon signed-rank test. Quantitatively, we compared the signal-to-noise ratios (SNRs) of the liver parenchyma, lesion-to-nonlesion contrast-to-noise ratios (CNRs) and apparent diffusion coefficient (ADC) values of the liver parenchyma and liver tumor by the paired t-test. Results: The average scores of image quality for sharpness of liver contour, image noise, and chemical shift artifacts were significantly higher for FB-DWI than RT-DWI (P < 0.05). SNRs, CNRs, and ADC values of the liver parenchyma and tumors did not differ significantly between the 2 DWI methods. Conclusion: Compared with RT-DWI, the optimized FB-DWI provided better spatial resolution, fewer artifacts, and comparable SNRs, lesion-to-nonlesion CNRs, and ADC values.

UR - http://www.scopus.com/inward/record.url?scp=84929303791&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929303791&partnerID=8YFLogxK

U2 - 10.2463/mrms.2014-0032

DO - 10.2463/mrms.2014-0032

M3 - Article

C2 - 25740235

AN - SCOPUS:84929303791

VL - 14

SP - 123

EP - 132

JO - Magnetic Resonance in Medical Sciences

JF - Magnetic Resonance in Medical Sciences

SN - 1347-3182

IS - 2

ER -