Oral administration of hot water extracts of Chlorella vulgaris reduces IgE production against milk casein in mice

T. Hasegawa, K. Ito, S. Ueno, S. Kumamoto, Y. Ando, A. Yamada, K. Nomoto, Y. Yasunobu

    研究成果: ジャーナルへの寄稿学術誌査読

    48 被引用数 (Scopus)

    抄録

    Hot water extract of Chlorella vulgaris (CVE) is a biological response modifier (BRM) which enhances resistance to Listeria monocytogenes through augmentation of helper T cell type 1 (Th1) responses producing gamma-interferon (γIFN). We show here that oral administration of CVE in mice suppressed the production of immunoglobulin (Ig)E against casein antigen accompanied by increased γIFN and IL-12 mRNA expression. Oral administration of CVE enhanced Th1 response to casein in the spleen of casein immunized mice. CVE may be useful for prevention of allergic diseases with a predominant Th2 response. Copyright (C) 1999 International Society for Immunopharmacology.

    本文言語英語
    ページ(範囲)311-323
    ページ数13
    ジャーナルInternational Journal of Immunopharmacology
    21
    5
    DOI
    出版ステータス出版済み - 5月 1999

    !!!All Science Journal Classification (ASJC) codes

    • 免疫学
    • 薬理学

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