Oral flora composition and its connection to oral health

研究成果: ジャーナルへの寄稿評論記事

2 引用 (Scopus)

抄録

More than 700 species of commensal bacteria inhabit the human oral cavity, of which many have been of keen interest due to their pathogenicity in oral diseases (e.g., dental caries and periodontal diseases); however, the interactions between the pathogens and the remaining commensal bacteria are not well known, thus preventing us from understanding the genuine etiologies of oral diseases. To overcome this challenge, it is essential to comprehensively identify the species compositions of individual oral flora in order to associate them with various conditions of oral health and understand the virulence derived from the oral flora community. In this review, we refer to modern molecular genetic technologies, such as terminal restriction fragment length polymorphism, DNA microarray and pyrosequencing analyses using bioinformatics. We also discuss their potential to further our comprehension of the complexities of floral composition.

元の言語英語
ページ(範囲)206-212
ページ数7
ジャーナルjournal of oral biosciences
53
発行部数3
DOI
出版物ステータス出版済み - 1 1 2011

Fingerprint

Mouth Diseases
Oral Health
Virulence
Health
Bacteria
Stomatognathic Diseases
Dental Caries
Periodontal Diseases
Microarray Analysis
Oligonucleotide Array Sequence Analysis
Computational Biology
Chemical analysis
Restriction Fragment Length Polymorphisms
Mouth
Molecular Biology
Bioelectric potentials
Pathogens
Bioinformatics
Microarrays
Technology

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Dentistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)

これを引用

Oral flora composition and its connection to oral health. / Yamashita, Yoshihisa; Takeshita, Toru.

:: journal of oral biosciences, 巻 53, 番号 3, 01.01.2011, p. 206-212.

研究成果: ジャーナルへの寄稿評論記事

@article{732a321d6b3d43bab818787b899e20ab,
title = "Oral flora composition and its connection to oral health",
abstract = "More than 700 species of commensal bacteria inhabit the human oral cavity, of which many have been of keen interest due to their pathogenicity in oral diseases (e.g., dental caries and periodontal diseases); however, the interactions between the pathogens and the remaining commensal bacteria are not well known, thus preventing us from understanding the genuine etiologies of oral diseases. To overcome this challenge, it is essential to comprehensively identify the species compositions of individual oral flora in order to associate them with various conditions of oral health and understand the virulence derived from the oral flora community. In this review, we refer to modern molecular genetic technologies, such as terminal restriction fragment length polymorphism, DNA microarray and pyrosequencing analyses using bioinformatics. We also discuss their potential to further our comprehension of the complexities of floral composition.",
author = "Yoshihisa Yamashita and Toru Takeshita",
year = "2011",
month = "1",
day = "1",
doi = "10.2330/joralbiosci.53.206",
language = "English",
volume = "53",
pages = "206--212",
journal = "Journal of Oral Biosciences",
issn = "1349-0079",
publisher = "Japanese Association for Oral Biology",
number = "3",

}

TY - JOUR

T1 - Oral flora composition and its connection to oral health

AU - Yamashita, Yoshihisa

AU - Takeshita, Toru

PY - 2011/1/1

Y1 - 2011/1/1

N2 - More than 700 species of commensal bacteria inhabit the human oral cavity, of which many have been of keen interest due to their pathogenicity in oral diseases (e.g., dental caries and periodontal diseases); however, the interactions between the pathogens and the remaining commensal bacteria are not well known, thus preventing us from understanding the genuine etiologies of oral diseases. To overcome this challenge, it is essential to comprehensively identify the species compositions of individual oral flora in order to associate them with various conditions of oral health and understand the virulence derived from the oral flora community. In this review, we refer to modern molecular genetic technologies, such as terminal restriction fragment length polymorphism, DNA microarray and pyrosequencing analyses using bioinformatics. We also discuss their potential to further our comprehension of the complexities of floral composition.

AB - More than 700 species of commensal bacteria inhabit the human oral cavity, of which many have been of keen interest due to their pathogenicity in oral diseases (e.g., dental caries and periodontal diseases); however, the interactions between the pathogens and the remaining commensal bacteria are not well known, thus preventing us from understanding the genuine etiologies of oral diseases. To overcome this challenge, it is essential to comprehensively identify the species compositions of individual oral flora in order to associate them with various conditions of oral health and understand the virulence derived from the oral flora community. In this review, we refer to modern molecular genetic technologies, such as terminal restriction fragment length polymorphism, DNA microarray and pyrosequencing analyses using bioinformatics. We also discuss their potential to further our comprehension of the complexities of floral composition.

UR - http://www.scopus.com/inward/record.url?scp=80052703585&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052703585&partnerID=8YFLogxK

U2 - 10.2330/joralbiosci.53.206

DO - 10.2330/joralbiosci.53.206

M3 - Review article

VL - 53

SP - 206

EP - 212

JO - Journal of Oral Biosciences

JF - Journal of Oral Biosciences

SN - 1349-0079

IS - 3

ER -