Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength

Nguyen Xuan Thanh Tram, Michito Maruta, Kanji Tusru, Shigeki Matsuya, Kunio Ishikawa

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We have established a processing method to fabricate three-dimensional porous carbonate apatite (CO3Ap) with interconnected porous structure and improved mechanical strength. Briefly, porous CO3Ap materials were produced via phosphorization of porous calcite precursor in hydrothermal condition. In order to make porous calcite precursor, negative replication of modified polyurethane foam template was conducted. In this study, an in vivo behavior of that porous CO3Ap was evaluated. The interconnected porous CO3Ap material was implanted in the tibia of Japanese male rabbits and removed after a period of 6 months. Micro-computed tomography (μ-CT) scanner and histological analysis were used to characterize the bone formation response of the porous CO3Ap. The results suggest that porous CO3Ap with enhanced mechanical strength was not only osteoconductive but also bioresorbable therefore it could be used as bone substitute material.

本文言語英語
ホスト出版物のタイトルBioceramics 27
編集者Ika Dewi Ana, Kuwat Triyana
出版社Trans Tech Publications Ltd
ページ23-26
ページ数4
ISBN(印刷版)9783035710403
DOI
出版ステータス出版済み - 1 1 2016
イベント27th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, 2015 - Bali, インドネシア
継続期間: 10 27 201510 29 2015

出版物シリーズ

名前Key Engineering Materials
696
ISSN(印刷版)1013-9826
ISSN(電子版)1662-9795

その他

その他27th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, 2015
Countryインドネシア
CityBali
Period10/27/1510/29/15

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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