Osteoid osteoma of mandibular bone: Case report and review of the literature

takashi maehara, Yuka Murakami, Shintarou Kawano, Yurie Mikami, Tamotsu Kiyoshima, Toru Chikui, Noriko Kakizoe, Ryusuke Munemura, Seiji Nakamura

研究成果: ジャーナルへの寄稿記事

抄録

Osteoid osteoma is a benign bone-forming tumor and characterized by its limited growth potential, not exceeding 2 cm. The radiological hallmark of this tumor is a nidus, which is a small round area of relative radiolucency. Osteoid osteoma can involve any bone but is most commonly found in long bones and is extremely rare in the head and neck region. This disease characteristically presents with dull pain, worse at night, and sometimes relieved with NSAIDs. A 24-year-old Japanese woman presented with spontaneous pain and tenderness on the lingual side of her mandibular second molar on the right side. The patient reported that her pain had gradually increased, becoming more continuous and severe and no longer responding to NSAIDs. An initial panoramic radiograph revealed an oval, internally non-uniform, somewhat obscure boundaries in the right mandible. Computed tomography (CT) scan revealed a sclerotic lesion with a delineated central calcified nidus surrounded by a radiolucent band. The interior of the nidus was a non-uniform, irregularly shaped area of high absorption. The nidus was removed with intralesional curettage under general anesthesia. The histopathology of the specimen consisted of actively proliferating osteoblasts mixed with an interlacing network of immature bone and osteoid trabeculae. Immunohistochemistry revealed that hardly detected osteoblasts or fibrous stromal cells with intense nuclear immunoreactivity for p16 and/or murine double minute 2 (mdm2). We thus distinguished the tumor from Low-grade central osteosarcoma (LGCO) with immunohistochemical findings. The histopathological diagnosis was thus osteoid osteoma.

元の言語英語
ページ(範囲)322-326
ページ数5
ジャーナルJournal of Oral and Maxillofacial Surgery, Medicine, and Pathology
31
発行部数5
DOI
出版物ステータス出版済み - 9 1 2019

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Osteoid Osteoma
Bone and Bones
Non-Steroidal Anti-Inflammatory Agents
Osteoblasts
Pain
Neoplasms
Curettage
Osteosarcoma
Stromal Cells
Mandible
Tongue
General Anesthesia
Neck
Immunohistochemistry
Head
Tomography
Growth

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Pathology and Forensic Medicine
  • Otorhinolaryngology

これを引用

Osteoid osteoma of mandibular bone : Case report and review of the literature. / maehara, takashi; Murakami, Yuka; Kawano, Shintarou; Mikami, Yurie; Kiyoshima, Tamotsu; Chikui, Toru; Kakizoe, Noriko; Munemura, Ryusuke; Nakamura, Seiji.

:: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 巻 31, 番号 5, 01.09.2019, p. 322-326.

研究成果: ジャーナルへの寄稿記事

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