Outcomes of prenatally diagnosed sacrococcygeal teratomas: The results of a Japanese nationwide survey

Noriaki Usui, Yoshihiro Kitano, Haruhiko Sago, Yutaka Kanamori, Akihiro Yoneda, Tomoo Nakamura, Shunsuke Nosaka, Mari Saito, Tomoaki Taguchi

研究成果: Contribution to journalArticle査読

25 被引用数 (Scopus)

抄録

Background/Purpose: Few large multicenter surveys have been performed on sacrococcygeal teratomas (SCTs) describing both the prenatal and postnatal courses. The aim of this study was to review and report on the prenatal surveillance and postnatal outcome of a large cohort of fetuses with SCTs in Japan. Methods: A nationwide retrospective cohort study was conducted on 97 fetuses prenatally diagnosed with SCTs between 2000 and 2009. The prenatal course, perinatal data, and postnatal outcome were reviewed. Results: Eleven pregnancies were terminated before 22 weeks of gestation. Of the 86 remaining fetuses, 3 died in utero, and 83 were delivered. Three infants died before surgery, and 8 infants died after excisional surgery. The overall mortality was 26%, with a mortality excluding terminations of 16%. The gestational age at delivery was younger than 28 weeks in 5, 28 to 31 weeks in 13, 32 to 36 weeks in 27, and 37 weeks or more in 37 cases, with mortality rates of 60%, 38%, 11%, and 0%, respectively. The tumor component was predominantly cystic in 54 and predominantly solid in 32 cases, with mortality rates of 2% and 33%, respectively. Conclusions: The overall mortality of prenatally diagnosed SCTs excluding terminations was 16%. Early delivery and predominantly solid component tumors were associated with an increased risk of mortality.

本文言語英語
ページ(範囲)441-447
ページ数7
ジャーナルJournal of Pediatric Surgery
47
3
DOI
出版ステータス出版済み - 3 2012

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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