Overview of BioBank Japan follow-up data in 32 diseases

Biobank Japan Cooperative Hospital Group

研究成果: Contribution to journalArticle査読

34 被引用数 (Scopus)

抄録

Background: We established a patient-oriented biobank, BioBank Japan, with information on approximately 200,000 patients, suffering from any of 47 common diseases. This follow-up survey focused on 32 diseases, potentially associated with poor vital prognosis, and collected patient survival information, including cause of death. We performed a survival analysis for all subjects to get an overview of BioBank Japan follow-up data. Methods: A total of 141,612 participants were included. The survival data were last updated in 2014. KaplaneMeier survival analysis was performed after categorizing subjects according to sex, age group, and disease status. Relative survival rates were estimated using a survival-rate table of the Japanese general population. Results: Of 141,612 subjects (56.48% male) with 1,087,434 person-years and a 97.0% follow-up rate, 35,482 patients died during follow-up. Mean age at enrollment was 64.24 years for male subjects and 63.98 years for female subjects. The 5-year and 10-year relative survival rates for all subjects were 0.944 and 0.911, respectively, with a median follow-up duration of 8.40 years. Patients with pancreatic cancer had the least favorable prognosis (10-year relative survival: 0.184) and patients with dyslipidemia had the most favorable prognosis (1.013). The most common cause of death was malignant neoplasms. A number of subjects died from diseases other than their registered disease(s).

本文言語英語
ページ(範囲)S22-S28
ジャーナルJournal of epidemiology
27
3
DOI
出版ステータス出版済み - 2017

All Science Journal Classification (ASJC) codes

  • 疫学

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