Palladium-catalyzed synthesis of diaryl ketones from aldehydes and (hetero)aryl halides via C-H bond activation

Takayuki Wakaki, Takaya Togo, Daisuke Yoshidome, Yoichiro Kuninobu, Motomu Kanai

研究成果: Contribution to journalArticle査読

46 被引用数 (Scopus)

抄録

We developed a palladium-catalyzed C-H transformation that enabled the synthesis of ketones from aldehydes and (hetero)aryl halides. The use of picolinamide ligands was key to achieving the transformation. Heteroaryl ketones, as well as diaryl ketones, were synthesized in good to excellent yields, even in gram-scale, using this reaction. Results of density functional theory (DFT) calculations support the C-H bond activation pathway.

本文言語英語
ページ(範囲)3123-3128
ページ数6
ジャーナルACS Catalysis
8
4
DOI
出版ステータス出版済み - 4 6 2018

All Science Journal Classification (ASJC) codes

  • 触媒
  • 化学 (全般)

フィンガープリント

「Palladium-catalyzed synthesis of diaryl ketones from aldehydes and (hetero)aryl halides via C-H bond activation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル