Pancreatic somatostatinoma diagnosed preoperatively

Report of a case

Yasuhisa Mori, Norihiro Sato, Ryuta Taniguchi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Mitsuhiro Nakamoto, Masashi Taguchi, Koji Yamaguchi

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

抄録

Context Somatostatinoma is a rare neoplasm of the pancreas. Preoperative diagnosis is often difficult. Case report We report a 72-year-old woman with a pancreatic head tumor measuring 37 mm in diameter, and enlargement of the lymph nodes on the anterior surface of the pancreatic head and the posterior surface of the horizontal part of the duodenum. Laboratory data showed an elevated plasma somatostatin concentration. Examination of a biopsy specimen of the pancreatic head mass obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) showed histopathological features of a neuroendocrine tumor. Immunohistochemical staining showed that the tumor cells were positive for somatostatin, leading to a preoperative diagnosis of pancreatic somatostatinoma. The patient underwent pylorus-preserving pancreaticoduodenectomy. The plasma somatostatin concentration decreased progressively after surgery. Conclusions A rare case of pancreatic somatostatinoma with lymph node metastases was presented. Immunohistochemical analysis of a biopsy specimen obtained by EUS-FNA was useful for preoperative diagnosis.

元の言語英語
ページ(範囲)66-71
ページ数6
ジャーナルJournal of the Pancreas
15
発行部数1
出版物ステータス出版済み - 1 1 2014
外部発表Yes

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Somatostatinoma
Somatostatin
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Lymph Nodes
Biopsy
Pancreaticoduodenectomy
Neuroendocrine Tumors
Pylorus
Pancreatic Neoplasms
Duodenum
Neoplasms
Staining and Labeling
Neoplasm Metastasis

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

これを引用

Mori, Y., Sato, N., Taniguchi, R., Tamura, T., Minagawa, N., Shibao, K., ... Yamaguchi, K. (2014). Pancreatic somatostatinoma diagnosed preoperatively: Report of a case. Journal of the Pancreas, 15(1), 66-71.

Pancreatic somatostatinoma diagnosed preoperatively : Report of a case. / Mori, Yasuhisa; Sato, Norihiro; Taniguchi, Ryuta; Tamura, Toshihisa; Minagawa, Noritaka; Shibao, Kazunori; Higure, Aiichiro; Nakamoto, Mitsuhiro; Taguchi, Masashi; Yamaguchi, Koji.

:: Journal of the Pancreas, 巻 15, 番号 1, 01.01.2014, p. 66-71.

研究成果: ジャーナルへの寄稿記事

Mori, Y, Sato, N, Taniguchi, R, Tamura, T, Minagawa, N, Shibao, K, Higure, A, Nakamoto, M, Taguchi, M & Yamaguchi, K 2014, 'Pancreatic somatostatinoma diagnosed preoperatively: Report of a case', Journal of the Pancreas, 巻. 15, 番号 1, pp. 66-71.
Mori Y, Sato N, Taniguchi R, Tamura T, Minagawa N, Shibao K その他. Pancreatic somatostatinoma diagnosed preoperatively: Report of a case. Journal of the Pancreas. 2014 1 1;15(1):66-71.
Mori, Yasuhisa ; Sato, Norihiro ; Taniguchi, Ryuta ; Tamura, Toshihisa ; Minagawa, Noritaka ; Shibao, Kazunori ; Higure, Aiichiro ; Nakamoto, Mitsuhiro ; Taguchi, Masashi ; Yamaguchi, Koji. / Pancreatic somatostatinoma diagnosed preoperatively : Report of a case. :: Journal of the Pancreas. 2014 ; 巻 15, 番号 1. pp. 66-71.
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abstract = "Context Somatostatinoma is a rare neoplasm of the pancreas. Preoperative diagnosis is often difficult. Case report We report a 72-year-old woman with a pancreatic head tumor measuring 37 mm in diameter, and enlargement of the lymph nodes on the anterior surface of the pancreatic head and the posterior surface of the horizontal part of the duodenum. Laboratory data showed an elevated plasma somatostatin concentration. Examination of a biopsy specimen of the pancreatic head mass obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) showed histopathological features of a neuroendocrine tumor. Immunohistochemical staining showed that the tumor cells were positive for somatostatin, leading to a preoperative diagnosis of pancreatic somatostatinoma. The patient underwent pylorus-preserving pancreaticoduodenectomy. The plasma somatostatin concentration decreased progressively after surgery. Conclusions A rare case of pancreatic somatostatinoma with lymph node metastases was presented. Immunohistochemical analysis of a biopsy specimen obtained by EUS-FNA was useful for preoperative diagnosis.",
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AU - Shibao, Kazunori

AU - Higure, Aiichiro

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