Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity

Tsutomu Iwamoto, Mariko Ono, Makiko Arakaki, Takashi Nakamura, Aya Yamada, Satoshi Fukumoto

研究成果: Chapter in Book/Report/Conference proceedingChapter

1 被引用数 (Scopus)

抄録

Gap junctional communications play a crucial role for organogenesis including cartilage development. Pannexin 3 (Panx3) belongs to the new member of the gap junction pannexin family. However, the expression and function of Panx3 have not been cleared. Here, we demonstrate that Panx3 is expressed in cartridge, and regulates chondrocyte differentiation in vitro cell culture. Our observations indicate that Panx3 plays a crucial role for the differentiation of chondrocyte, and suggest that Panx3 is a key molecule for cartilage development.

本文言語英語
ホスト出版物のタイトルInterface Oral Health Science 2011
出版社Springer Japan
ページ346-348
ページ数3
ISBN(電子版)9784431540700
ISBN(印刷版)9784431540694
DOI
出版ステータス出版済み - 1 1 2012
外部発表はい

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

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