Parotid gland carcinoma

32 years' experience from a single institute

T. Nakano, Ryuji Yasumatsu, R. Kogo, K. Hashimoto, Kaori Asai, Shoichi Ohga, H. Yamamoto, T. Nakashima, Takashi Nakagawa

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

抄録

Background Parotid gland carcinoma is a rare and complicated histopathological classification. Therefore, assembling a sufficient number of cases with long-term outcomes in a single institute can present a challenge.Method The medical records of 108 parotid gland carcinoma patients who were treated at Kyushu University Hospital, Fukuoka, Japan, between 1983 and 2014 were reviewed. The survival outcomes were analysed according to clinicopathological findings.Results Forty-six patients had low clinical stage tumours (I-II), and 62 patients had high clinical stage tumours (III-IV). Fifty-two, 10 and 46 patients had low-, intermediate-and high-grade tumours, respectively. Twenty-seven of 65 cases had positive surgical margins. In high clinical stage and intermediate-to high-grade tumours, adjuvant radiation therapy was correlated with local recurrence-free survival (p = 0.0244). Intermediate-to high-grade tumours and positive surgical margins were significantly associated with disease-specific survival in multivariate analysis (p = 0.0002 and p = 0.0058).Conclusion The results of this study show that adjuvant radiation therapy is useful for improved local control in patients with high clinical stage and intermediate-to high-grade tumours.

元の言語英語
ページ(範囲)604-609
ページ数6
ジャーナルJournal of Laryngology and Otology
133
発行部数7
DOI
出版物ステータス出版済み - 7 1 2019

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Parotid Gland
Carcinoma
Neoplasms
Survival
Radiotherapy
Medical Records
Japan
Multivariate Analysis
Recurrence

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

これを引用

Parotid gland carcinoma : 32 years' experience from a single institute. / Nakano, T.; Yasumatsu, Ryuji; Kogo, R.; Hashimoto, K.; Asai, Kaori; Ohga, Shoichi; Yamamoto, H.; Nakashima, T.; Nakagawa, Takashi.

:: Journal of Laryngology and Otology, 巻 133, 番号 7, 01.07.2019, p. 604-609.

研究成果: ジャーナルへの寄稿記事

Nakano, T. ; Yasumatsu, Ryuji ; Kogo, R. ; Hashimoto, K. ; Asai, Kaori ; Ohga, Shoichi ; Yamamoto, H. ; Nakashima, T. ; Nakagawa, Takashi. / Parotid gland carcinoma : 32 years' experience from a single institute. :: Journal of Laryngology and Otology. 2019 ; 巻 133, 番号 7. pp. 604-609.
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AU - Nakano, T.

AU - Yasumatsu, Ryuji

AU - Kogo, R.

AU - Hashimoto, K.

AU - Asai, Kaori

AU - Ohga, Shoichi

AU - Yamamoto, H.

AU - Nakashima, T.

AU - Nakagawa, Takashi

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N2 - Background Parotid gland carcinoma is a rare and complicated histopathological classification. Therefore, assembling a sufficient number of cases with long-term outcomes in a single institute can present a challenge.Method The medical records of 108 parotid gland carcinoma patients who were treated at Kyushu University Hospital, Fukuoka, Japan, between 1983 and 2014 were reviewed. The survival outcomes were analysed according to clinicopathological findings.Results Forty-six patients had low clinical stage tumours (I-II), and 62 patients had high clinical stage tumours (III-IV). Fifty-two, 10 and 46 patients had low-, intermediate-and high-grade tumours, respectively. Twenty-seven of 65 cases had positive surgical margins. In high clinical stage and intermediate-to high-grade tumours, adjuvant radiation therapy was correlated with local recurrence-free survival (p = 0.0244). Intermediate-to high-grade tumours and positive surgical margins were significantly associated with disease-specific survival in multivariate analysis (p = 0.0002 and p = 0.0058).Conclusion The results of this study show that adjuvant radiation therapy is useful for improved local control in patients with high clinical stage and intermediate-to high-grade tumours.

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