Parotid gland carcinoma: 32 years' experience from a single institute

T. Nakano, R. Yasumatsu, Ryunosuke Kogo, K. Hashimoto, K. Asai, S. Ohga, H. Yamamoto, Torahiko Nakashima, T. Nakagawa

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

Background Parotid gland carcinoma is a rare and complicated histopathological classification. Therefore, assembling a sufficient number of cases with long-term outcomes in a single institute can present a challenge.Method The medical records of 108 parotid gland carcinoma patients who were treated at Kyushu University Hospital, Fukuoka, Japan, between 1983 and 2014 were reviewed. The survival outcomes were analysed according to clinicopathological findings.Results Forty-six patients had low clinical stage tumours (I-II), and 62 patients had high clinical stage tumours (III-IV). Fifty-two, 10 and 46 patients had low-, intermediate-and high-grade tumours, respectively. Twenty-seven of 65 cases had positive surgical margins. In high clinical stage and intermediate-to high-grade tumours, adjuvant radiation therapy was correlated with local recurrence-free survival (p = 0.0244). Intermediate-to high-grade tumours and positive surgical margins were significantly associated with disease-specific survival in multivariate analysis (p = 0.0002 and p = 0.0058).Conclusion The results of this study show that adjuvant radiation therapy is useful for improved local control in patients with high clinical stage and intermediate-to high-grade tumours.

本文言語英語
ページ(範囲)604-609
ページ数6
ジャーナルJournal of Laryngology and Otology
133
7
DOI
出版ステータス出版済み - 7 1 2019

All Science Journal Classification (ASJC) codes

  • 耳鼻咽喉科学

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