Pathophysiological roles of NADPH oxidase/Nox family proteins in the vascular system review and perspective

Tetsuro Ago, Junya Kuroda, Masahiro Kamouchi, Junichi Sadoshima, Takanari Kitazono

研究成果: Contribution to journalReview article査読

73 被引用数 (Scopus)

抄録

It has been established that oxidative stress plays a crucial role in the development and progression of vascular diseases. Besides the mitochondria, the NADPH oxidase/Nox family proteins are now thought to be important origins of the reactive oxygen species that underlie various vascular disease states, such as hypertension, atherosclerosis, angiogenesis, and ischemia/reperfusion injury. This review summarizes the basis of vascular Nox proteins and discusses their pathophysiological roles in the vascular system.

本文言語英語
ページ(範囲)1791-1800
ページ数10
ジャーナルCirculation Journal
75
8
DOI
出版ステータス出版済み - 8 2011

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

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