Pemetrexed-induced edema of the eyelid

Takayasu Kurata, Kenji Tamura, Isamu Okamoto, Taroh Satoh, Kazuhiko Nakagawa, Masahiro Fukuoka

研究成果: ジャーナルへの寄稿学術誌査読

12 被引用数 (Scopus)

抄録

Pemetrexed is a novel antimetabolite that targets multiple enzymes in the folate pathway, and has exhibited clear antitumor activities in the treatment of malignant pleural mesothelioma and non-small cell lung cancer. Although many adverse events of pemetrexed, such as bone marrow suppression, have been reported, edema of the eyelid has been previously reported in only one case (0.2%, n = 519), according to the Pemetrexed Clinical Investigator's Brochure, April 2005 version. We experienced a patient who developed the valuable edema of the eyelid. We believe that medical oncologists should be aware of this rare adverse event, although the mechanism responsible for it is not yet known.

本文言語英語
ページ(範囲)241-242
ページ数2
ジャーナルLung Cancer
54
2
DOI
出版ステータス出版済み - 11月 2006
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 呼吸器内科
  • 癌研究

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