Peptide-Based Switching of Polymer Fluorescence in Aqueous phase

Hirotaka Ejima, Hiromi Kikuchi, Hisao Matsuno, Hirofumi Yajima, Takeshi Serizawa

研究成果: Contribution to journalArticle査読

11 被引用数 (Scopus)

抄録

The phage display method on water-soluble and commonly used poly-(2-methoxy-5-propyloxysulfonate-1,4-phenylenevinylene) (mpsPPV) were studied. mpsPPV was immobilized using a layer-by-layer (LbL) assembly technique with poly(diallyldimethylammonium chloride) (PDDA) to obtain water-insoluble polyelectrolyte multilayer films, with an outermost surface composed of mpsPPV, on a glass substrate. The assembly process and the stability of the obtained LbL films were monitored by quartz-crystal microbalance (QCM) measurement. A linear 12-mer peptide library solution was applied to this LbL film. The LbL film was considered to be stable throughout the phage display experiment, because the frequency shift was negligible after immersion in ethanol and Tris-buffered saline. It was suggested that π-π interactions were predominant between the peptide and mpsPPV.

本文言語英語
ページ(範囲)6032-6034
ページ数3
ジャーナルChemistry of Materials
22
22
DOI
出版ステータス出版済み - 11 23 2010
外部発表はい

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)
  • Materials Chemistry

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