TY - JOUR
T1 - Periodic discharges with high frequency oscillations recorded from a cerebellar gangliocytoma in an epileptic infant
AU - Mukae, Nobutaka
AU - Morioka, Takato
AU - Torio, Michiko
AU - Sakai, Yasunari
AU - Shimogawa, Takafumi
AU - Sakata, Ayumi
AU - Suzuki, Satoshi O.
AU - Mizoguchi, Masahiro
N1 - Publisher Copyright:
© 2021 Published by Scientific Scholar on behalf of Surgical Neurology International.
PY - 2021/3/17
Y1 - 2021/3/17
N2 - Background: Subcortical epilepsies associated with developmental tumors in the cerebellum are rarely experienced. As supportive evidence of the intrinsic epileptogenicity of cerebellar tumors, previous electroencephalogram (EEG) studies with intratumoral depth electrodes demonstrated epileptiform or ictal discharges. Recent studies have demonstrated that high frequency oscillations (HFOs) can be regarded as a new biomarker of epileptogenesis and ictogenesis; however, there are few evidence about HFOs in cases of epilepsy associated with cerebellar tumors. Case Description: A 6-month-old Japanese male infant presented to our hospital with drug resistant epilepsy. We underwent subtotal resection of a cerebellar gangliocytoma and obtained good seizure outcomes. Intraoperative EEG in the tumor depicted HFOs in the form of ripples, riding on periodic discharges. Conclusion: Our findings provide further supportive evidence for the intrinsic epileptogenicity of cerebellar tumors.
AB - Background: Subcortical epilepsies associated with developmental tumors in the cerebellum are rarely experienced. As supportive evidence of the intrinsic epileptogenicity of cerebellar tumors, previous electroencephalogram (EEG) studies with intratumoral depth electrodes demonstrated epileptiform or ictal discharges. Recent studies have demonstrated that high frequency oscillations (HFOs) can be regarded as a new biomarker of epileptogenesis and ictogenesis; however, there are few evidence about HFOs in cases of epilepsy associated with cerebellar tumors. Case Description: A 6-month-old Japanese male infant presented to our hospital with drug resistant epilepsy. We underwent subtotal resection of a cerebellar gangliocytoma and obtained good seizure outcomes. Intraoperative EEG in the tumor depicted HFOs in the form of ripples, riding on periodic discharges. Conclusion: Our findings provide further supportive evidence for the intrinsic epileptogenicity of cerebellar tumors.
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U2 - 10.25259/SNI_28_2021
DO - 10.25259/SNI_28_2021
M3 - Article
AN - SCOPUS:85103545270
VL - 12
JO - Surgical Neurology International
JF - Surgical Neurology International
SN - 2152-7806
M1 - A3
ER -