Periodic discharges with high frequency oscillations recorded from a cerebellar gangliocytoma in an epileptic infant

Nobutaka Mukae, Takato Morioka, Michiko Torio, Yasunari Sakai, Takafumi Shimogawa, Ayumi Sakata, Satoshi O. Suzuki, Masahiro Mizoguchi

研究成果: Contribution to journalArticle査読

抄録

Background: Subcortical epilepsies associated with developmental tumors in the cerebellum are rarely experienced. As supportive evidence of the intrinsic epileptogenicity of cerebellar tumors, previous electroencephalogram (EEG) studies with intratumoral depth electrodes demonstrated epileptiform or ictal discharges. Recent studies have demonstrated that high frequency oscillations (HFOs) can be regarded as a new biomarker of epileptogenesis and ictogenesis; however, there are few evidence about HFOs in cases of epilepsy associated with cerebellar tumors. Case Description: A 6-month-old Japanese male infant presented to our hospital with drug resistant epilepsy. We underwent subtotal resection of a cerebellar gangliocytoma and obtained good seizure outcomes. Intraoperative EEG in the tumor depicted HFOs in the form of ripples, riding on periodic discharges. Conclusion: Our findings provide further supportive evidence for the intrinsic epileptogenicity of cerebellar tumors.

本文言語英語
論文番号A3
ジャーナルSurgical Neurology International
12
DOI
出版ステータス出版済み - 3 17 2021

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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