Peripheral neuropathy, myelopathy, cerebellar ataxia, and subclinical optic neuropathy associated with copper deficiency occurring 23 years after total gastrectomy

Meiko Inaba, Takako Torii, Koji Shinoda, Ryo Yamasaki, Yasumasa Ohyagi, Jun Ichi Kira

研究成果: Contribution to journalLetter査読

2 被引用数 (Scopus)

抄録

We report a 61-year-old man with slowly progressive gait disturbance and paresthesia in the lower extremities following a total gastrectomy for gastric cancer 23 years previously. The patient presented with hyperreflexia, peripheral sensory neuropathy, and cerebellar ataxia. Magnetic resonance imaging showed atrophy of the cerebellum, and electrophysiological findings suggested the presence of disorder in both sides of the pyramidal tract, dorsal column, peripheral nerves, and optic nerve. Laboratory findings revealed anemia, neutropenia, and a remarkably low serum copper level (10 μg/dl; normal: 68-128). His serum vitamin E was slightly low and his serum vitamin B 12 was within the normal limits. After administering an oral copper supplement, his symptoms improved with normalization of the serum copper level. We need to pay attention to myeloneuropathy caused by copper deficiency if the patient has a past history of total gastrectomy.

本文言語英語
ページ(範囲)412-416
ページ数5
ジャーナルClinical Neurology
51
6
DOI
出版ステータス出版済み - 6 2011

All Science Journal Classification (ASJC) codes

  • 臨床神経学

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