Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA

H. Sugiyama, M. Watanabe, H. Taji, Y. Yamamoto, I. Ito

研究成果: Contribution to journalArticle査読

18 被引用数 (Scopus)

抄録

Quisqualate- and kainate-preferring glutamate receptors were studied in Xenopus oocytes injected with rat and chick brain mRNA. All ligands effective at ionotropic quisqualate sites, agonists as well as antagonists, were found to inhibit kainate responses. Ionotropic quisqualate and kainate responses were distinguished by γ-l-glutamylglycine but not by its d-isomer. No difference was detected between responses induced by rat brain mRNA and chick brain mRNA, suggesting that the properties on non-N-methyl-d-aspartate-type glutamate receptors of rat and chick brains are essentially the same.

本文言語英語
ページ(範囲)164-167
ページ数4
ジャーナルNeuroscience Research
7
2
DOI
出版ステータス出版済み - 11 1989

All Science Journal Classification (ASJC) codes

  • 神経科学(全般)

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