Physical comorbidities in older adults receiving antidepressants in Asia

Xiao Mei Zhong, Min Dong, Fei Wang, Qinge Zhang, Gabor S. Ungvari, Chee H. Ng, Helen F.K. Chiu, Tian Mei Si, Kang Sim, Ajit Avasthi, Sandeep Grover, Mian Yoon Chong, Kok Yoon Chee, Shigenobu Kanba, Min Soo Lee, Shu Yu Yang, Pichet Udomratn, Roy A. Kallivayalil, Andi J. Tanra, Margarita M. MaramisWinston W. Shen, Norman Sartorius, Rathi Mahendran, Chay Hoon Tan, Naotaka Shinfuku, Yu Tao Xiang

研究成果: ジャーナルへの寄稿学術誌査読

3 被引用数 (Scopus)


Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.

出版ステータス出版済み - 9月 2018

!!!All Science Journal Classification (ASJC) codes

  • 老年学
  • 老年医学
  • 精神医学および精神衛生


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