A novel type of polymersome formed through a self-assembly of polyion complex of block copolymers was firstly designed as "PICsome". The simplicity of the process of solute encapsulation into the PICsome indicates the feasibility of the PICsome as a container for water-soluble macromolecules. The PICsome with encapsulated FITC-Dex was appreciably stable in physiological buffer as observed by confocal laser scanning microscope (CLSM) even after three months standing at ambient temperature. Furthermore, the CLSM results indicate that the PICsome membrane has a semipermeable character to allow the penetration of only small molecules.
|出版ステータス||出版済み - 2006|
|イベント||55th SPSJ Annual Meeting - Nagoya, 日本|
継続期間: 5 24 2006 → 5 26 2006
|その他||55th SPSJ Annual Meeting|
|Period||5/24/06 → 5/26/06|
All Science Journal Classification (ASJC) codes