Plasma concentration of human atrial natriuretic hormone in patients with connective tissue diseases

M. Yasuda, D. Yasuda, Katsuhiko Tomooka, M. Nobunaga

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抄録

Atrial natriuretic peptide (ANP), a peptide released from the cardiac atria, compensates blood volume expansion by its diuretic, natriuretic and vasoactive properties. We measured human plasma ANP(hANP) levels in patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and progressive systemic sclerosis (PSS) and found that their values were higher than those of healthy controls. In SLE patients, hANP levels correlated with serum creatinine concentration and the patients with proteinuria showed high levels of hANP. Administration of large amount of corticosteroid as a remission induction of the patients with SLE caused high levels of hANP. In patients with PSS, %FEV1 showed strong inverse correlations between hANP levels, and the patients with an enlarged second curvature of the heart had high levels of hANP. In patients with RA, no significant correlation was found between hANP levels and clinical variables including patients' age.

元の言語英語
ページ(範囲)231-235
ページ数5
ジャーナルClinical Rheumatology
12
発行部数2
DOI
出版物ステータス出版済み - 6 1 1993

Fingerprint

Natriuretic Agents
Connective Tissue Diseases
Atrial Natriuretic Factor
Systemic Lupus Erythematosus
Diffuse Scleroderma
Rheumatoid Arthritis
Remission Induction
Blood Volume
Proteinuria
Diuretics
Creatinine
Adrenal Cortex Hormones
Peptides

All Science Journal Classification (ASJC) codes

  • Rheumatology

これを引用

Plasma concentration of human atrial natriuretic hormone in patients with connective tissue diseases. / Yasuda, M.; Yasuda, D.; Tomooka, Katsuhiko; Nobunaga, M.

:: Clinical Rheumatology, 巻 12, 番号 2, 01.06.1993, p. 231-235.

研究成果: ジャーナルへの寄稿記事

@article{bd89503958f244428a18dbc1464b4484,
title = "Plasma concentration of human atrial natriuretic hormone in patients with connective tissue diseases",
abstract = "Atrial natriuretic peptide (ANP), a peptide released from the cardiac atria, compensates blood volume expansion by its diuretic, natriuretic and vasoactive properties. We measured human plasma ANP(hANP) levels in patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and progressive systemic sclerosis (PSS) and found that their values were higher than those of healthy controls. In SLE patients, hANP levels correlated with serum creatinine concentration and the patients with proteinuria showed high levels of hANP. Administration of large amount of corticosteroid as a remission induction of the patients with SLE caused high levels of hANP. In patients with PSS, {\%}FEV1 showed strong inverse correlations between hANP levels, and the patients with an enlarged second curvature of the heart had high levels of hANP. In patients with RA, no significant correlation was found between hANP levels and clinical variables including patients' age.",
author = "M. Yasuda and D. Yasuda and Katsuhiko Tomooka and M. Nobunaga",
year = "1993",
month = "6",
day = "1",
doi = "10.1007/BF02231533",
language = "English",
volume = "12",
pages = "231--235",
journal = "Clinical Rheumatology",
issn = "0770-3198",
publisher = "Springer London",
number = "2",

}

TY - JOUR

T1 - Plasma concentration of human atrial natriuretic hormone in patients with connective tissue diseases

AU - Yasuda, M.

AU - Yasuda, D.

AU - Tomooka, Katsuhiko

AU - Nobunaga, M.

PY - 1993/6/1

Y1 - 1993/6/1

N2 - Atrial natriuretic peptide (ANP), a peptide released from the cardiac atria, compensates blood volume expansion by its diuretic, natriuretic and vasoactive properties. We measured human plasma ANP(hANP) levels in patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and progressive systemic sclerosis (PSS) and found that their values were higher than those of healthy controls. In SLE patients, hANP levels correlated with serum creatinine concentration and the patients with proteinuria showed high levels of hANP. Administration of large amount of corticosteroid as a remission induction of the patients with SLE caused high levels of hANP. In patients with PSS, %FEV1 showed strong inverse correlations between hANP levels, and the patients with an enlarged second curvature of the heart had high levels of hANP. In patients with RA, no significant correlation was found between hANP levels and clinical variables including patients' age.

AB - Atrial natriuretic peptide (ANP), a peptide released from the cardiac atria, compensates blood volume expansion by its diuretic, natriuretic and vasoactive properties. We measured human plasma ANP(hANP) levels in patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and progressive systemic sclerosis (PSS) and found that their values were higher than those of healthy controls. In SLE patients, hANP levels correlated with serum creatinine concentration and the patients with proteinuria showed high levels of hANP. Administration of large amount of corticosteroid as a remission induction of the patients with SLE caused high levels of hANP. In patients with PSS, %FEV1 showed strong inverse correlations between hANP levels, and the patients with an enlarged second curvature of the heart had high levels of hANP. In patients with RA, no significant correlation was found between hANP levels and clinical variables including patients' age.

UR - http://www.scopus.com/inward/record.url?scp=0027181964&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027181964&partnerID=8YFLogxK

U2 - 10.1007/BF02231533

DO - 10.1007/BF02231533

M3 - Article

C2 - 8358985

AN - SCOPUS:0027181964

VL - 12

SP - 231

EP - 235

JO - Clinical Rheumatology

JF - Clinical Rheumatology

SN - 0770-3198

IS - 2

ER -