Plasmid deoxyribonucleic acid and translucent-to-opaque variation in Mycobacterium intracellulare 103

Y. Mizuguchi, M. Fukunaga, Hatsumi Taniguchi

研究成果: ジャーナルへの寄稿記事

31 引用 (Scopus)

抄録

After treatment with mitomycin C and other antibacterial agents, a translucent, smooth-colony-forming mycobacterium, isolated from sputum and designated as M. intracellulare strain 103, gave rise to variants forming opaque colonies. These opaque variants were more sensitive streptomycin, kanamycin, viomycin, and rifampin than were the wild-type translucent variants. Plasmid deoxyribonucleic acids taken from translucent strain cells and from cells of certain opaque variants were analyzed by agarose gel electrophoresis. Two plasmids of molecular weights of approximately 2 X 106 and 50 X 106, respectively, were found in the wild-type translucent cells; one of them, the 2 X 106-molecular-weight plasmid, was always missing from deoxyribonucleic acids of the opaque variant cells. The results suggested that translucent colonial appearance and antibiotic resistance of the strain are plasmid-determined functions.

元の言語英語
ページ(範囲)656-659
ページ数4
ジャーナルJournal of Bacteriology
146
発行部数2
出版物ステータス出版済み - 1981
外部発表Yes

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Mycobacterium avium Complex
Plasmids
DNA
Viomycin
Molecular Weight
Kanamycin
Agar Gel Electrophoresis
Mitomycin
Streptomycin
Rifampin
Mycobacterium
Microbial Drug Resistance
Sputum
Anti-Bacterial Agents

All Science Journal Classification (ASJC) codes

  • Applied Microbiology and Biotechnology
  • Immunology

これを引用

Plasmid deoxyribonucleic acid and translucent-to-opaque variation in Mycobacterium intracellulare 103. / Mizuguchi, Y.; Fukunaga, M.; Taniguchi, Hatsumi.

:: Journal of Bacteriology, 巻 146, 番号 2, 1981, p. 656-659.

研究成果: ジャーナルへの寄稿記事

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