Pneumocystis carinii pneumonia in Diamond-Blackfan anemia: The necessity of chemoprophylaxis for young infants

A. Nomura, S. Ohga, Y. Asaka, H. Takada, F. Nakao, K. Kusuhara, T. Hara

研究成果: ジャーナルへの寄稿学術誌査読

2 被引用数 (Scopus)

抄録

Two infants with Diamond-Blackfan anemia (DBA) developed Pneumocystis carinii pneumonia during corticosteroid (CS) therapy. Both patients showed the typical prodrome of tachypnea and fever, and the chest X-ray findings of interstitial infiltration, along with high serum levels of β-D-glucan and undetectable levels of endotoxin. The PCR study of bronchoalveolar lavage fluid was positive for P. carinii DNA in a 4-month-old infant, although it was not available in the previous case of a 2-month-old infant. No other causative agents were defined. They had no predisposing immunodeficiency diseases. Prophylaxis against P. carinii infection must be considered for young infants with DBA during the first CS therapy.

本文言語英語
ページ(範囲)7-11
ページ数5
ジャーナルInternational Journal of Pediatric Hematology/Oncology
7
1
出版ステータス出版済み - 2000

!!!All Science Journal Classification (ASJC) codes

  • 小児科学、周産期医学および子どもの健康
  • 血液学
  • 癌研究

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