Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos

Zhenhai Du, Hui Zheng, Yumiko K. Kawamura, Ke Zhang, Johanna Gassler, Sean Powell, Qianhua Xu, Zili Lin, Kai Xu, Qian Zhou, Evgeniy A. Ozonov, Nathalie Véron, Bo Huang, Lijia Li, Guang Yu, Ling Liu, Wan Kin Au Yeung, Peizhe Wang, Lei Chang, Qiujun WangAibin He, Yujie Sun, Jie Na, Qingyuan Sun, Hiroyuki Sasaki, Kikuë Tachibana, Antoine H.F.M. Peters, Wei Xie

研究成果: Contribution to journalArticle査読

24 被引用数 (Scopus)

抄録

In mammals, germ cells undergo a series of events to give rise to haploid gametes. The dynamics of meiotic chromatin architecture still remain poorly understood. By applying Hi-C to mouse oocytes, Du et al. reveal a unique Polycomb-regulated chromatin architecture, which adds a new perspective to the non-canonical oocyte epigenomes.

本文言語英語
ページ(範囲)825-839.e7
ジャーナルMolecular Cell
77
4
DOI
出版ステータス出版済み - 2 20 2020

All Science Journal Classification (ASJC) codes

  • 分子生物学
  • 細胞生物学

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