Polymerization of diacetylene in casting parallel and anti-parallel β-sheet

Shiro Yasutake, Takeshi Mori, Keiji Minagawa, Masami Tanaka

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抜粋

In the β sheet structure of the peptide, the distance among the β-strands are 5 Å. This distance corresponds with distance among the monomer units of diacetylene and diene. Therefore the β-sheet will be able to be cross-linked by introducing these monomer units into the diacetylene and diene into peptide that formed β-sheet by using this. In this work, we synthesized peptide 1-4. Peptide 1 and 2 were design to form anti-parallel β-sheet alone. On the other hand, peptide 3 and 4 were design to form parallel β-sheet by mixing them. Polymerization of 1 and 2 was conducted by UV irradiation. After the polymerization, UV-vis spectra of 1 and 2 in dichloroacetic acid had an absorbance at 573 nm that originates in poly diacetylene. The result of FT-IR measurement of them showed disappearance of a peak at 2250 cm-1 that originates in diacetylene. Amide I region suggested that the peptides formed anti-parallel β-sheet and random coil. Therefore, it seemed that polymerization occurred in the β-sheet formed part.

元の言語英語
ホスト出版物のタイトル54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
ページ198
ページ数1
54
エディション1
出版物ステータス出版済み - 2005
外部発表Yes
イベント54th SPSJ Annual Meeting 2005 - Yokohama, 日本
継続期間: 5 25 20055 27 2005

その他

その他54th SPSJ Annual Meeting 2005
日本
Yokohama
期間5/25/055/27/05

All Science Journal Classification (ASJC) codes

  • Engineering(all)

フィンガープリント Polymerization of diacetylene in casting parallel and anti-parallel β-sheet' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Yasutake, S., Mori, T., Minagawa, K., & Tanaka, M. (2005). Polymerization of diacetylene in casting parallel and anti-parallel β-sheet. : 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan (1 版, 巻 54, pp. 198)