Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

H. Nakashima, M. Akahoshi, Y. Tanaka, K. Yamaoka, E. Ogami, S. Nagano, Y. Arinobu, H. Niiro, T. Otsuka, Y. Niho

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

抄録

Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

元の言語英語
ページ(範囲)1142-1144
ページ数3
ジャーナルRheumatology
38
発行部数11
DOI
出版物ステータス出版済み - 11 1999

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Interleukin-10 Receptors
Systemic Lupus Erythematosus
Complementary DNA
Genotype
Genes
Gene Frequency
Restriction Fragment Length Polymorphisms
Reverse Transcription
Healthy Volunteers
Polymerase Chain Reaction

All Science Journal Classification (ASJC) codes

  • Rheumatology
  • Pharmacology (medical)

これを引用

Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus. / Nakashima, H.; Akahoshi, M.; Tanaka, Y.; Yamaoka, K.; Ogami, E.; Nagano, S.; Arinobu, Y.; Niiro, H.; Otsuka, T.; Niho, Y.

:: Rheumatology, 巻 38, 番号 11, 11.1999, p. 1142-1144.

研究成果: ジャーナルへの寄稿記事

Nakashima, H. ; Akahoshi, M. ; Tanaka, Y. ; Yamaoka, K. ; Ogami, E. ; Nagano, S. ; Arinobu, Y. ; Niiro, H. ; Otsuka, T. ; Niho, Y. / Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus. :: Rheumatology. 1999 ; 巻 38, 番号 11. pp. 1142-1144.
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T1 - Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

AU - Nakashima, H.

AU - Akahoshi, M.

AU - Tanaka, Y.

AU - Yamaoka, K.

AU - Ogami, E.

AU - Nagano, S.

AU - Arinobu, Y.

AU - Niiro, H.

AU - Otsuka, T.

AU - Niho, Y.

PY - 1999/11

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N2 - Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

AB - Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

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