Polysaccharide schizophyllan-based plasm id DNA carrier

T. Nagasaki, T. Satoh, A. Uno, M. Hojo, K. Koumoto, M. Mizu, K. Sakurai, S. Shinkai

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

The development of polysaccharide schizophyllan-based plasmid DNA carrier was analyzed. Amine-introduced cationic schizophyllan (SPG) carriers were prepared using ethanolamine, spermidine, spermine, and N,N'-bis(3-aminopropyl)- 1,3-propanediamine. It was found that transfection efficiency was dependent on cation/anion ratios, with carriers having SPG as the backbone showing the highest transfection efficiency with C/A ratios of 10-15. It was observed that transfection efficiency of the 80,000 Da derivative was about eight times greater than that of PEI.

本文言語英語
ホスト出版物のタイトルTransactions - 7th World Biomaterials Congress
ページ数1
出版ステータス出版済み - 12 1 2004
イベントTransactions - 7th World Biomaterials Congress - Sydney, オーストラリア
継続期間: 5 17 20045 21 2004

出版物シリーズ

名前Transactions - 7th World Biomaterials Congress

その他

その他Transactions - 7th World Biomaterials Congress
Countryオーストラリア
CitySydney
Period5/17/045/21/04

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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