Possible binding sites for inositol 1,4,5-trisphosphate in macrophages

Toyohiro Ishimatsu, Yuichi Kimura, Tetsuro Ikebe, Koji Yamaguchi, Toshitaka Koga, Masato Hirata

研究成果: Contribution to journalArticle

7 引用 (Scopus)

抜粋

We reported that an arylazide derivative of inositol 1,4,5-trisphosphate (InsP3) caused irreversible InsP3-induced Ca2+ release from saponin-permeabilized macrophages after photoirradiation(1). To determine the specific receptors for InsP3, presumably present on the endoplastic reticulum, we synthesized isotope-labeled arylazide derivatives of InsP3; InsP3 was coupled with p-azidobenzoyl [3h]β -alanine InsP3-[3h]ABβ A ) or p-[125i]azidosalicyl β-alanine (InsP3-[125I]ASβ A). We report here that three proteins may be associated with the Ca2+ releasing mechanism, in photoirradiated saponin-permeabilized macrophages and in the microsomal fraction.

元の言語英語
ページ(範囲)1173-1180
ページ数8
ジャーナルBiochemical and Biophysical Research Communications
155
発行部数3
DOI
出版物ステータス出版済み - 9 30 1988

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

フィンガープリント Possible binding sites for inositol 1,4,5-trisphosphate in macrophages' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用