Postoperative development of sarcopenia is a strong predictor of a poor prognosis in patients with adenocarcinoma of the esophagogastric junction and upper gastric cancer

Kensuke Kudou, Hiroshi Saeki, Yuichiro Nakashima, Shun Sasaki, Tomoko Jogo, Kosuke Hirose, Qingjiang Hu, Yasuo Tsuda, Koichi Kimura, Ryota Nakanishi, Nobuhide Kubo, Kouji Andou, Eiji Oki, Tetsuo Ikeda, Yoshihiko Maehara

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

抄録

Background: There were few studies assessed the postoperative sarcopenia in patients with cancers. The objective of present study was to assess whether postoperative development of sarcopenia could predict a poor prognosis in patients with adenocarcinoma of esophagogastric junction, (AEG) and upper gastric cancer (UGC). Methods: Patients with AEG and UGC who were judged as non-sarcopenic before surgery were reassessed the presence of postoperative development of sarcopenia 6 months after surgery. Patients were divided into the development group or non-development group, and clinicopathological factors and prognosis between these two groups were analyzed. Results: The 5-year overall survival rates were significantly poorer in the development group than non-development group (68.0% vs. 92.6%, P = 0.0118). Multivariate analyses showed that postoperative development of sarcopenia was an independent prognostic factor for poor overall survival (P = 0.0237). Conclusions: Postoperative development of sarcopenia was associated with a poor prognosis in patients with AEG and UGC.

元の言語英語
ページ(範囲)757-763
ページ数7
ジャーナルAmerican Journal of Surgery
217
発行部数4
DOI
出版物ステータス出版済み - 4 1 2019

Fingerprint

Sarcopenia
Esophagogastric Junction
Stomach Neoplasms
Adenocarcinoma
Multivariate Analysis
Survival Rate
Survival
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery

これを引用

Postoperative development of sarcopenia is a strong predictor of a poor prognosis in patients with adenocarcinoma of the esophagogastric junction and upper gastric cancer. / Kudou, Kensuke; Saeki, Hiroshi; Nakashima, Yuichiro; Sasaki, Shun; Jogo, Tomoko; Hirose, Kosuke; Hu, Qingjiang; Tsuda, Yasuo; Kimura, Koichi; Nakanishi, Ryota; Kubo, Nobuhide; Andou, Kouji; Oki, Eiji; Ikeda, Tetsuo; Maehara, Yoshihiko.

:: American Journal of Surgery, 巻 217, 番号 4, 01.04.2019, p. 757-763.

研究成果: ジャーナルへの寄稿記事

Kudou, Kensuke ; Saeki, Hiroshi ; Nakashima, Yuichiro ; Sasaki, Shun ; Jogo, Tomoko ; Hirose, Kosuke ; Hu, Qingjiang ; Tsuda, Yasuo ; Kimura, Koichi ; Nakanishi, Ryota ; Kubo, Nobuhide ; Andou, Kouji ; Oki, Eiji ; Ikeda, Tetsuo ; Maehara, Yoshihiko. / Postoperative development of sarcopenia is a strong predictor of a poor prognosis in patients with adenocarcinoma of the esophagogastric junction and upper gastric cancer. :: American Journal of Surgery. 2019 ; 巻 217, 番号 4. pp. 757-763.
@article{1e932cc7db024853bb15cbb9429c342e,
title = "Postoperative development of sarcopenia is a strong predictor of a poor prognosis in patients with adenocarcinoma of the esophagogastric junction and upper gastric cancer",
abstract = "Background: There were few studies assessed the postoperative sarcopenia in patients with cancers. The objective of present study was to assess whether postoperative development of sarcopenia could predict a poor prognosis in patients with adenocarcinoma of esophagogastric junction, (AEG) and upper gastric cancer (UGC). Methods: Patients with AEG and UGC who were judged as non-sarcopenic before surgery were reassessed the presence of postoperative development of sarcopenia 6 months after surgery. Patients were divided into the development group or non-development group, and clinicopathological factors and prognosis between these two groups were analyzed. Results: The 5-year overall survival rates were significantly poorer in the development group than non-development group (68.0{\%} vs. 92.6{\%}, P = 0.0118). Multivariate analyses showed that postoperative development of sarcopenia was an independent prognostic factor for poor overall survival (P = 0.0237). Conclusions: Postoperative development of sarcopenia was associated with a poor prognosis in patients with AEG and UGC.",
author = "Kensuke Kudou and Hiroshi Saeki and Yuichiro Nakashima and Shun Sasaki and Tomoko Jogo and Kosuke Hirose and Qingjiang Hu and Yasuo Tsuda and Koichi Kimura and Ryota Nakanishi and Nobuhide Kubo and Kouji Andou and Eiji Oki and Tetsuo Ikeda and Yoshihiko Maehara",
year = "2019",
month = "4",
day = "1",
doi = "10.1016/j.amjsurg.2018.07.003",
language = "English",
volume = "217",
pages = "757--763",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Postoperative development of sarcopenia is a strong predictor of a poor prognosis in patients with adenocarcinoma of the esophagogastric junction and upper gastric cancer

AU - Kudou, Kensuke

AU - Saeki, Hiroshi

AU - Nakashima, Yuichiro

AU - Sasaki, Shun

AU - Jogo, Tomoko

AU - Hirose, Kosuke

AU - Hu, Qingjiang

AU - Tsuda, Yasuo

AU - Kimura, Koichi

AU - Nakanishi, Ryota

AU - Kubo, Nobuhide

AU - Andou, Kouji

AU - Oki, Eiji

AU - Ikeda, Tetsuo

AU - Maehara, Yoshihiko

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Background: There were few studies assessed the postoperative sarcopenia in patients with cancers. The objective of present study was to assess whether postoperative development of sarcopenia could predict a poor prognosis in patients with adenocarcinoma of esophagogastric junction, (AEG) and upper gastric cancer (UGC). Methods: Patients with AEG and UGC who were judged as non-sarcopenic before surgery were reassessed the presence of postoperative development of sarcopenia 6 months after surgery. Patients were divided into the development group or non-development group, and clinicopathological factors and prognosis between these two groups were analyzed. Results: The 5-year overall survival rates were significantly poorer in the development group than non-development group (68.0% vs. 92.6%, P = 0.0118). Multivariate analyses showed that postoperative development of sarcopenia was an independent prognostic factor for poor overall survival (P = 0.0237). Conclusions: Postoperative development of sarcopenia was associated with a poor prognosis in patients with AEG and UGC.

AB - Background: There were few studies assessed the postoperative sarcopenia in patients with cancers. The objective of present study was to assess whether postoperative development of sarcopenia could predict a poor prognosis in patients with adenocarcinoma of esophagogastric junction, (AEG) and upper gastric cancer (UGC). Methods: Patients with AEG and UGC who were judged as non-sarcopenic before surgery were reassessed the presence of postoperative development of sarcopenia 6 months after surgery. Patients were divided into the development group or non-development group, and clinicopathological factors and prognosis between these two groups were analyzed. Results: The 5-year overall survival rates were significantly poorer in the development group than non-development group (68.0% vs. 92.6%, P = 0.0118). Multivariate analyses showed that postoperative development of sarcopenia was an independent prognostic factor for poor overall survival (P = 0.0237). Conclusions: Postoperative development of sarcopenia was associated with a poor prognosis in patients with AEG and UGC.

UR - http://www.scopus.com/inward/record.url?scp=85049629832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049629832&partnerID=8YFLogxK

U2 - 10.1016/j.amjsurg.2018.07.003

DO - 10.1016/j.amjsurg.2018.07.003

M3 - Article

C2 - 30005807

AN - SCOPUS:85049629832

VL - 217

SP - 757

EP - 763

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 4

ER -