TY - JOUR
T1 - Prediction of Postoperative Complications Following Elective Surgery in Elderly Patients with Colorectal Cancer Using the Comprehensive Geriatric Assessment
AU - Mokutani, Yukako
AU - Mizushima, Tsunekazu
AU - Yamasaki, Makoto
AU - Rakugi, Hiromi
AU - Doki, Yuichiro
AU - Mori, Masaki
N1 - Publisher Copyright:
© 2016 S. Karger AG, Basel.
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Aims: The study aims to determine whether the Comprehensive Geriatric Assessment (CGA) could predict complications of colorectal cancer (CRC) surgery and identify the problems. So we compared the prognostic value of the CGA with patient characteristics and determined predictive scores. Methods: A total of 156 patients aged 75 years and older, who underwent surgery for CRC at Osaka University Hospital, were enrolled. Each patient was examined by the CGA prospectively, and all postoperative complications were obtained from the medical records. The CGA included the Barthel Index (BI), Vitality Index, instrumental activities of daily living (iADL), Mini-Mental State Examination (MMSE) and Geriatric Depression Score (GDS). All elements were retrospectively compared in patients with or without postoperative complications, including delirium, surgical site infection and ileus. Results: Overall, postoperative complications developed in 76 patients (48.7%). The BI and MMSE were associated with the incidence of complications, and BI, iADL, MMSE and GDS were significantly related with delirium. Multivariate logistic analysis identified the MMSE as a significant determinant of postoperative complications after adjusting for other determined predictive scores including the prognostic nutritional index and performance status. Conclusion: The CGA was a useful predictor of postoperative complications in elderly patients when administered before surgery for CRC.
AB - Aims: The study aims to determine whether the Comprehensive Geriatric Assessment (CGA) could predict complications of colorectal cancer (CRC) surgery and identify the problems. So we compared the prognostic value of the CGA with patient characteristics and determined predictive scores. Methods: A total of 156 patients aged 75 years and older, who underwent surgery for CRC at Osaka University Hospital, were enrolled. Each patient was examined by the CGA prospectively, and all postoperative complications were obtained from the medical records. The CGA included the Barthel Index (BI), Vitality Index, instrumental activities of daily living (iADL), Mini-Mental State Examination (MMSE) and Geriatric Depression Score (GDS). All elements were retrospectively compared in patients with or without postoperative complications, including delirium, surgical site infection and ileus. Results: Overall, postoperative complications developed in 76 patients (48.7%). The BI and MMSE were associated with the incidence of complications, and BI, iADL, MMSE and GDS were significantly related with delirium. Multivariate logistic analysis identified the MMSE as a significant determinant of postoperative complications after adjusting for other determined predictive scores including the prognostic nutritional index and performance status. Conclusion: The CGA was a useful predictor of postoperative complications in elderly patients when administered before surgery for CRC.
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U2 - 10.1159/000446709
DO - 10.1159/000446709
M3 - Article
C2 - 27250985
AN - SCOPUS:84977662788
VL - 33
SP - 470
EP - 477
JO - Digestive Surgery
JF - Digestive Surgery
SN - 0253-4886
IS - 6
ER -